NMDAR2A Antikörper (AA 23-165)

Produktnummer ABIN5611284

Produktdetails anti-NMDAR2A Antikörper

Target: NMDAR2A (GRIN2A) (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2a (GRIN2A))

Bindungsspezifität: AA 23-165

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser NMDAR2A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS), Neutralization (Neut)

Aufreinigung: purified

Immunogen: Purified recombinant fragment of human GRIN2A (AA: extra 23-165) expressed in E. coli.

Klon: 3G10F9

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: N/A, FCM: 1:200 - 1:400, IHC: N/A

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: 4°C, -20°C for long term storage

Details zu NMDAR2A

Target: NMDAR2A (GRIN2A) (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2a (GRIN2A))

Andere Bezeichnung: GRIN2A (GRIN2A Produkte)

Synonyme: NMDAR2A antikoerper, nr2a antikoerper, GRIN2A antikoerper, EPND antikoerper, GluN2A antikoerper, NR2A antikoerper, glutamate ionotropic receptor NMDA type subunit 2A antikoerper, glutamate receptor, ionotropic, N-methyl D-aspartate 2A L homeolog antikoerper, glutamate receptor ionotropic, NMDA 2A antikoerper, glutamate receptor, ionotropic, NMDA2A (epsilon 1) antikoerper, GRIN2A antikoerper, grin2a.L antikoerper, LOC100438553 antikoerper, Grin2a antikoerper

Hintergrund:

Description: This gene encodes a member of the glutamate-gated ion channel protein family. The encoded protein is an N-methyl-D-aspartate (NMDA) receptor subunit. NMDA receptors are both ligand-gated and voltage-dependent, and are involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. These receptors are permeable to calcium ions, and activation results in a calcium influx into post-synaptic cells, which results in the activation of several signaling cascades. Disruption of this gene is associated with focal epilepsy and speech disorder with or without mental retardation. Alternative splicing results in multiple transcript variants.

Aliases: LKS, EPND, FESD, NR2A, GluN2A, NMDAR2A

Molekulargewicht: 165.3 kDa

Gen-ID: 2903

HGNC: 2903

Pathways: Synaptic Membrane, Regulation of long-term Neuronal Synaptic Plasticity