DNAJC2 Antikörper (AA 1-140)

Produktnummer ABIN1679553

Produktdetails anti-DNAJC2 Antikörper

Target: DNAJC2 (DnaJ (Hsp40) Homolog, Subfamily C, Member 2 (DNAJC2))

Bindungsspezifität: AA 1-140

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DNAJC2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: MLLLPSAADG RGTAITHALT SASTLCQVEP VGRWFEAFVK RRNRNASASF QELEDKKELS EESEDEELQL EEFPMLKTLD PKDWKNQDHY AVLGLGHVRY KATQRQIKAA HKAMVLKHHP DKRKAAGEPI KEGDNDYFTC

Kreuzreaktivität: Human, Maus

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-140 of human DNAJC2 (NP_055192.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu DNAJC2

Target: DNAJC2 (DnaJ (Hsp40) Homolog, Subfamily C, Member 2 (DNAJC2))

Andere Bezeichnung: DNAJC2 (DNAJC2 Produkte)

Synonyme: zrf1 antikoerper, ZRF1 antikoerper, MPHOSPH11 antikoerper, MPP11 antikoerper, ZUO1 antikoerper, AU020218 antikoerper, MIDA1 antikoerper, Zrf1 antikoerper, Zrf2 antikoerper, zgc:85671 antikoerper, DnaJ heat shock protein family (Hsp40) member C2 antikoerper, DnaJ (Hsp40) homolog, subfamily C, member 2 antikoerper, dnajc2 antikoerper, DNAJC2 antikoerper, Dnajc2 antikoerper

Hintergrund: This gene is a member of the M-phase phosphoprotein (MPP) family. The gene encodes a phosphoprotein with a J domain and a Myb DNA-binding domain which localizes to both the nucleus and the cytosol. The protein is capable of forming a heterodimeric complex that associates with ribosomes, acting as a molecular chaperone for nascent polypeptide chains as they exit the ribosome. This protein was identified as a leukemia-associated antigen and expression of the gene is upregulated in leukemic blasts. Also, chromosomal aberrations involving this gene are associated with primary head and neck squamous cell tumors. This gene has a pseudogene on chromosome 6. Alternatively spliced variants which encode different protein isoforms have been described.,DNAJC2,MPHOSPH11,MPP11,ZRF1,ZUO1,Epigenetics & Nuclear Signaling,RNA Binding,Cancer,Tumor immunology,Tumor-associated antigens,Signal Transduction,Immunology & Inflammation,DNAJC2

Molekulargewicht: 65 kDa/71 kDa

Gen-ID: 27000

UniProt: Q99543

Pathways: Chromatin Binding