DNAJC2 Antikörper (AA 1-140)

Produktnummer ABIN7150549

Produktdetails anti-DNAJC2 Antikörper

Target: DNAJC2 (DnaJ (Hsp40) Homolog, Subfamily C, Member 2 (DNAJC2))

Bindungsspezifität: AA 1-140

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DNAJC2 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Kreuzreaktivität: Human

Aufreinigung: Antigen Affinity Purified

Immunogen: Recombinant Human DnaJ homolog subfamily C member 2 protein (1-140AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu DNAJC2

Target: DNAJC2 (DnaJ (Hsp40) Homolog, Subfamily C, Member 2 (DNAJC2))

Andere Bezeichnung: DNAJC2 (DNAJC2 Produkte)

Synonyme: zrf1 antikoerper, ZRF1 antikoerper, MPHOSPH11 antikoerper, MPP11 antikoerper, ZUO1 antikoerper, AU020218 antikoerper, MIDA1 antikoerper, Zrf1 antikoerper, Zrf2 antikoerper, zgc:85671 antikoerper, DnaJ heat shock protein family (Hsp40) member C2 antikoerper, DnaJ (Hsp40) homolog, subfamily C, member 2 antikoerper, dnajc2 antikoerper, DNAJC2 antikoerper, Dnajc2 antikoerper

Hintergrund:

Background: Acts both as a chaperone in the cytosol and as a chromatin regulator in the nucleus. When cytosolic, acts as a molecular chaperone: component of the ribosome-associated complex (RAC), a complex involved in folding or maintaining nascent polypeptides in a folding-competent state. In the RAC complex, stimulates the ATPase activity of the ribosome-associated pool of Hsp70-type chaperones HSPA14 that bind to the nascent polypeptide chain. When nuclear, mediates the switching from polycomb-repressed genes to an active state: specifically recruited at histone H2A ubiquitinated at \\\'Lys-119\\\' (H2AK119ub), and promotes the displacement of the polycomb PRC1 complex from chromatin, thereby facilitating transcription activation. Specifically binds DNA sequence 5\\\'-GTCAAGC-3\\\'.

Aliases: AU020218 antibody, DnaJ (Hsp40) homolog subfamily C member 2 antibody, DnaJ homolog subfamily C member 2 antibody, Dnajc2 antibody, DNJC2_HUMAN antibody, M phase phosphoprotein 11 antibody, M-phase phosphoprotein 11 antibody, MGC105894 antibody, MIDA1 antibody, MPHOSPH11 antibody, MPP11 antibody, OTTMUSP00000031226 antibody, ZRF1 antibody, Zrf2 antibody, ZUO1 antibody, Zuotin related factor 1 antibody, Zuotin related factor 2 antibody, Zuotin-related factor 1 antibody

UniProt: Q99543

Pathways: Chromatin Binding