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CD3 epsilon Antikörper

CD3E Reaktivität: Maus FACS Wirt: Hamster Monoclonal 145-2C11 unconjugated
Produktnummer ABIN161365
  • Target Alle CD3 epsilon (CD3E) Antikörper anzeigen
    CD3 epsilon (CD3E)
    Reaktivität
    • 201
    • 164
    • 44
    • 41
    • 18
    • 8
    • 8
    • 8
    • 7
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Maus
    Wirt
    • 139
    • 105
    • 36
    • 24
    • 16
    • 10
    • 1
    Hamster
    Klonalität
    • 205
    • 120
    • 6
    Monoklonal
    Konjugat
    • 120
    • 28
    • 28
    • 18
    • 13
    • 7
    • 7
    • 7
    • 6
    • 6
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
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    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CD3 epsilon Antikörper ist unkonjugiert
    Applikation
    • 228
    • 154
    • 85
    • 83
    • 69
    • 66
    • 32
    • 27
    • 22
    • 19
    • 14
    • 13
    • 13
    • 13
    • 8
    • 6
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Spezifität
    Mouse CD3
    Aufreinigung
    Purified
    Immunogen
    H-2Kb sp . Fusion Partner: Murine myeloma cell line SP2/0 . Donor: BALB/c
    Klon
    145-2C11
    Isotyp
    IgG
    Top Product
    Discover our top product CD3E Primärantikörper
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    0.5 µg/10 cells
    Lagerung
    4 °C
  • Target
    CD3 epsilon (CD3E)
    Andere Bezeichnung
    CD3e (CD3E Produkte)
    Synonyme
    cd3e antikoerper, CD3E antikoerper, t3e antikoerper, tcre antikoerper, AI504783 antikoerper, CD3 antikoerper, CD3epsilon antikoerper, T3e antikoerper, T3E antikoerper, TCRE antikoerper, CD3e molecule antikoerper, CD3 antigen, epsilon polypeptide antikoerper, cd3e antikoerper, CD3E antikoerper, Cd3e antikoerper
    Hintergrund
    Anti-mouse CD3 monoclonal antibody is specific for a 25 kDa protein component ( -T3) of the antigen specific T cell receptor on all mouse strains tested. The -T3 protein has been shown to be non-covalently associated on the cell surface heterodimer of the CD3 associated complex. This monoclonal antibody reacts with all mature T cells and can both activate and inhibit T cell function (1). This fact identifies -T3 as a cell surface protein involved in the transduction of activation signals. All peripheral T cells express this determinant however B cells and bone marrow cells have proven to be negative. Although the expression of this particular epitope on peripheral T cells is uniformly high, staining of thymocytes reveals distinct subpopulations of cells differing in the level of expression of this marker. This antibody will prove useful in studying the role of various components of the TCR complex in T cell activation and development, and will allow for the development of an animal model in which to investigate the immunoregulatory effects of in vivo administration of anti-CD3 antibodies, an area of obvious clinical
    Pathways
    T-Zell Rezeptor Signalweg, CXCR4-mediated Signaling Events, Ubiquitin Proteasome Pathway
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