HDAC4 Antikörper (Internal Region)

Produktnummer ABIN1607887

Produktdetails anti-HDAC4 Antikörper

Target: HDAC4 (Histone Deacetylase 4 (HDAC4))

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus, Ratte, Primate

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HDAC4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Fluorescence Microscopy (FM)

Kreuzreaktivität (Details): Cross reactivity with HDAC4 from other sources has not been determined.

Reinheit: Anti-HDAC4 was affinity purified from monospecific antiserum by immunoaffinity chromatography. This antibody is specific towards HDAC4. A BLAST analysis was used to suggest cross-reactivity with Human, Mouse, Rat, and Primate based on 100 % sequence homology.

Endotoxin-Niveau: Low Endotoxin : No

Immunogen: HDAC4 affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to the internal region of human HDAC4.
Immunogen Type: Peptide

Anwendungsinformationen

Applikationshinweise: Anti-HDAC4 antibody is useful for ELISA, immunohistochemistry, and Western Blot. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately ~140 kDa corresponding to the appropriate cell lysate or extract.
ELISA Dilution: 1:20.000 - 1:60.000
Immunohistochemistry Dilution: 1 mg/mL
IF Microscopy Dilution: 1:100-1:500
Western Blot Dilution: 1 mg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: 50 % (v/v) Glycerol

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store vial at -20 °C prior to opening. Aliquot contents and freeze at -20 °C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4 °C as an undiluted liquid. Dilute only prior to immediate use.

Haltbarkeit: Expiration date is six (6) months from date of opening.

Details zu HDAC4

Target: HDAC4 (Histone Deacetylase 4 (HDAC4))

Andere Bezeichnung: HDAC4 (HDAC4 Produkte)

Synonyme: CG1770 antikoerper, DHDAC4 antikoerper, Dmel\\CG1770 antikoerper, GC1770 antikoerper, HDAC antikoerper, HDAC4a antikoerper, dHDAC4 antikoerper, dmHDA405 antikoerper, hdac4 antikoerper, dana_GLEANR_19966 antikoerper, DanaGF18710 antikoerper, GF18710 antikoerper, HDAC4 antikoerper, AHO3 antikoerper, BDMR antikoerper, HA6116 antikoerper, HD4 antikoerper, HDAC-4 antikoerper, HDAC-A antikoerper, HDACA antikoerper, 4932408F19Rik antikoerper, AI047285 antikoerper, wu:fa96d08 antikoerper, wu:fc56f08 antikoerper, zgc:152701 antikoerper, histone deacetylase 4 antikoerper, hypothetical protein antikoerper, Histone deacetylase 4 antikoerper, GF18710 gene product from transcript GF18710-RC antikoerper, PTRG_03699 antikoerper, PGTG_15512 antikoerper, HDAC4 antikoerper, Dana\GF18710 antikoerper, Hdac4 antikoerper, hdac4 antikoerper

Hintergrund: HDAC4 is a 140 kD class II histone deacetylase similar to the yeast HDA1 protein. This nuclear protein operates in concert with histone acetyltransferases to control core histone acetylation in highly conserved lysine residues. HDAC activity has been associated with transcriptional repression and nucleosomal condensation. HDAC4 uses active nuclear export to shuttle between the nucleus and the cytoplasm. HDAC4 is modified by phosphorylation by CaM kinase I or IV. HDAC4 has been reported to interact with 14-3-3 in the cytoplasm and MEF2A, HDAC3, NcoR and SMRT in the nucleus. Anti-HDAC4 antibodies are ideal for researchers interested in Breast Cancer, Cancer, Cell Cycle and Replication, Chromatin Research, Epigenetics, and Histone Deacetylases research. Synonyms: HA6116, HDAC-A, HDACABDMR, HD4EC 3.5.1.98, histone deacetylase A, histone deacetylase 4, KIAA0288AHO3

Gen-ID: 9759

NCBI Accession: NP_006028

UniProt: P56524

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process