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HDAC4 Antikörper (AA 530-630)

HDAC4 Reaktivität: Human WB, IP Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN3020757
  • Target Alle HDAC4 Antikörper anzeigen
    HDAC4 (Histone Deacetylase 4 (HDAC4))
    Bindungsspezifität
    • 15
    • 14
    • 11
    • 9
    • 9
    • 8
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 530-630
    Reaktivität
    • 113
    • 52
    • 35
    • 6
    • 6
    • 4
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 101
    • 13
    • 1
    Kaninchen
    Klonalität
    • 102
    • 13
    Polyklonal
    Konjugat
    • 71
    • 8
    • 7
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser HDAC4 Antikörper ist unkonjugiert
    Applikation
    • 87
    • 51
    • 29
    • 15
    • 14
    • 13
    • 13
    • 10
    • 9
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP)
    Sequenz
    REHQALLDEP YLDRLPGQKE AHAQAGVQVK QEPIESDEEE AEPPREVEPG QRQPSEQELL FRQQALLLEQ QRIHQLRNYQ ASMEAAGIPV SFGGHRPLSR A
    Kreuzreaktivität
    Human, Maus
    Produktmerkmale
    Polyclonal Antibodies
    Aufreinigung
    Affinity purification
    Immunogen
    A synthetic peptide corresponding to a sequence within amino acids 530-630 of human HDAC4 (NP_006028.2).
    Isotyp
    IgG
    Top Product
    Discover our top product HDAC4 Primärantikörper
  • Applikationshinweise
    WB,1:500 - 1:2000,IP,1:50 - 1:100
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid freeze / thaw cycles
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    HDAC4 (Histone Deacetylase 4 (HDAC4))
    Andere Bezeichnung
    HDAC4 (HDAC4 Produkte)
    Hintergrund
    Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3.,HDAC4,AHO3,BDMR,HA6116,HD4,HDAC-4,HDAC-A,HDACA,Epigenetics & Nuclear Signaling,Nuclear Receptor Signaling,Signal Transduction,Cell Biology & Developmental Biology,Cell Cycle,G1/S Checkpoint,Notch Signaling Pathway,Wnt/β-Catenin Signaling Pathway,Immunology & Inflammation,NF-kB Signaling Pathway,Stem Cells,Cardiovascular,Heart,Hypertrophy,HDAC4
    Molekulargewicht
    106 kDa/119 kDa
    Gen-ID
    9759
    UniProt
    P56524
    Pathways
    Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process
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