NFASC Antikörper (N-Term)

Produktnummer ABIN1574089

Produktdetails anti-NFASC Antikörper

Target: NFASC (Neurofascin (NFASC))

Bindungsspezifität: N-Term

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NFASC Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Spezifität: Rabbit Anti-Neurofascin Polyclonal Antibody detects endogenous levels of rat and mouse Neurofascin protein. It is predicted to react with human neurofascin protein according to sequence homology.

Kreuzreaktivität (Details): Rabbit Anti-Neurofascin Polyclonal Antibody detects endogenous levels of rat and mouse Neurofascin protein. It is predicted to react with human neurofascin protein according to sequence homology.

Aufreinigung: Immunoaffinity chromatography

Immunogen: KLH-coupled synthetic peptide from amino terminal of human Neurofascin .

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Working concentrations for specific applications should be determined by the investigator. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product.

ELISA: 0.05-0.2 µg/mL Western blot: 1-2 µg/mLOther Applications: user-optimized

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: PBS, pH 7.4, containing 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: The antibody is stable in lyophilized form if stored at -20°C or below. The reconstituted antibody can be stored for 2-3 weeks at 2-8°C. For long term storage, aliquot and store at -20°C or below. Avoid repeated freezing and thawing cycles.

Details zu NFASC

Target: NFASC (Neurofascin (NFASC))

Andere Bezeichnung: Neurofascin (NFASC Produkte)

Synonyme: sc:d0205 antikoerper, NF antikoerper, NRCAML antikoerper, AA387016 antikoerper, D430023G06Rik antikoerper, mKIAA0756 antikoerper, neurofascin antikoerper, neurofascin homolog (chicken) a antikoerper, NFASC antikoerper, nfasca antikoerper, Nfasc antikoerper

Hintergrund: Neurofascin is one member of Li family which involves vertebrate L1, Ng-CAM, and Nr-CAM. Neurofascin protein is a nervous system cell adhesion molecule that contains six Ig domains and multiple fibronectin type III repeats in its extracellular region. Expression level of neurofascin is abundant in the nervous system during early development as well as in adult stage. Phosphorylation of the FIGQY tyrosine of neurofascin abolishes ankyrin binding and increases lateral mobility of neurofascin. Phospho-FIGQY neurofascin associates with doublecortin, which probably plays an important role in neuronal migration.Rabbit Anti-Neurofascin Polyclonal Antibody is developed in rabbit using a KLH-coupled synthetic peptide from amino terminal of human Neurofascin. (Swiss Prot: O94856).

Pathways: Cell-Cell Junction Organization