Cortactin Antikörper

Produktnummer ABIN1539851

Produktdetails anti-Cortactin Antikörper

Target: Cortactin (CTTN)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Cortactin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.

Immunogen: Purified His-tagged Cortactin protein(Fragment) was used to produced this monoclonal antibody.

Klon: 401CT8-6-3

Isotyp: IgM

Anwendungsinformationen

Applikationshinweise: WB: 1:1000~8000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Mouse monoclonal antibody supplied in crude ascites with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Cortactin Antibody(Ascites) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Haltbarkeit: 6 months

Details zu Cortactin

Target: Cortactin (CTTN)

Andere Bezeichnung: Cortactin (CTTN Produkte)

Synonyme: EMS1 antikoerper, 1110020L01Rik antikoerper, Ems1 antikoerper, Cttnb antikoerper, CG3637 antikoerper, Dmel\CG3637 antikoerper, cortactin antikoerper, cttn antikoerper, CTTN1 antikoerper, P85.25 antikoerper, Cttn antikoerper, ems1 antikoerper, CTTN antikoerper, cortactin antikoerper, CG3637 gene product from transcript CG3637-RD antikoerper, cortactin S homeolog antikoerper, cortactin L homeolog antikoerper, src substrate cortactin antikoerper, Src substrate cortactin antikoerper, CTTN antikoerper, Cttn antikoerper, Cortactin antikoerper, cttn.S antikoerper, cttn.L antikoerper, cttn antikoerper, CpipJ_CPIJ006351 antikoerper, Bm1_57220 antikoerper, LOC100533277 antikoerper

Hintergrund: This gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this gene contributes to tumor cell invasion and metastasis. Three splice variants that encode different isoforms have been identified for this gene.

Molekulargewicht: 61586

Gen-ID: 2017

NCBI Accession: NP_001171669, NP_005222, NP_612632

UniProt: Q14247

Pathways: MAPK Signalweg