DRAP1 Antikörper (N-Term)

Produktnummer ABIN1538849

Produktdetails anti-DRAP1 Antikörper

Target: DRAP1 (DR1-Associated Protein 1 (Negative Cofactor 2 Alpha) (DRAP1))

Bindungsspezifität: AA 1-29, N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DRAP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Homologie: B, M, Rat

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This DRAP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-29 amino acids from the N-terminal region of human DRAP1.

Klon: RB32124

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: DRAP1 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Haltbarkeit: 6 months

Details zu DRAP1

Target: DRAP1 (DR1-Associated Protein 1 (Negative Cofactor 2 Alpha) (DRAP1))

Andere Bezeichnung: DRAP1 (DRAP1 Produkte)

Synonyme: fb26e10 antikoerper, zgc:56003 antikoerper, zgc:77337 antikoerper, wu:fb26e10 antikoerper, DRAP1 antikoerper, 2310074H19Rik antikoerper, NC2-alpha antikoerper, DR1-associated protein 1 (negative cofactor 2 alpha) antikoerper, DR1 associated protein 1 antikoerper, Dr1 associated protein 1 (negative cofactor 2 alpha) antikoerper, Dr1 associated protein 1 antikoerper, drap1 antikoerper, DRAP1 antikoerper, Drap1 antikoerper

Hintergrund: Transcriptional repression is a general mechanism for regulating transcriptional initiation in organisms ranging from yeast to humans. Accurate initiation of transcription from eukaryotic protein-encoding genes requires the assembly of a large multiprotein complex consisting of RNA polymerase II and general transcription factors such as TFIIA, TFIIB, and TFIID. DR1 is a repressor that interacts with the TATA-binding protein (TBP) of TFIID and prevents the formation of an active transcription complex by precluding the entry of TFIIA and/or TFIIB into the preinitiation complex. The protein encoded by this gene is a corepressor of transcription that interacts with DR1 to enhance DR1-mediated repression. The interaction between this corepressor and DR1 is required for corepressor function and appears to stabilize the TBP-DR1-DNA complex.

Molekulargewicht: 22350

Gen-ID: 10589

NCBI Accession: NP_006433

UniProt: Q14919