DRAP1 Antikörper (N-Term)
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- Target Alle DRAP1 Antikörper anzeigen
- DRAP1 (DR1-Associated Protein 1 (Negative Cofactor 2 Alpha) (DRAP1))
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Bindungsspezifität
- AA 1-29, N-Term
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser DRAP1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Homologie
- B, M, Rat
- Aufreinigung
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogen
- This DRAP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-29 amino acids from the N-terminal region of human DRAP1.
- Klon
- RB32124
- Isotyp
- Ig Fraction
- Top Product
- Discover our top product DRAP1 Primärantikörper
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- Applikationshinweise
- WB: 1:1000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- DRAP1 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.
- Haltbarkeit
- 6 months
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- Target
- DRAP1 (DR1-Associated Protein 1 (Negative Cofactor 2 Alpha) (DRAP1))
- Andere Bezeichnung
- DRAP1 (DRAP1 Produkte)
- Synonyme
- fb26e10 antikoerper, zgc:56003 antikoerper, zgc:77337 antikoerper, wu:fb26e10 antikoerper, DRAP1 antikoerper, 2310074H19Rik antikoerper, NC2-alpha antikoerper, DR1-associated protein 1 (negative cofactor 2 alpha) antikoerper, DR1 associated protein 1 antikoerper, Dr1 associated protein 1 (negative cofactor 2 alpha) antikoerper, Dr1 associated protein 1 antikoerper, drap1 antikoerper, DRAP1 antikoerper, Drap1 antikoerper
- Hintergrund
- Transcriptional repression is a general mechanism for regulating transcriptional initiation in organisms ranging from yeast to humans. Accurate initiation of transcription from eukaryotic protein-encoding genes requires the assembly of a large multiprotein complex consisting of RNA polymerase II and general transcription factors such as TFIIA, TFIIB, and TFIID. DR1 is a repressor that interacts with the TATA-binding protein (TBP) of TFIID and prevents the formation of an active transcription complex by precluding the entry of TFIIA and/or TFIIB into the preinitiation complex. The protein encoded by this gene is a corepressor of transcription that interacts with DR1 to enhance DR1-mediated repression. The interaction between this corepressor and DR1 is required for corepressor function and appears to stabilize the TBP-DR1-DNA complex.
- Molekulargewicht
- 22350
- Gen-ID
- 10589
- NCBI Accession
- NP_006433
- UniProt
- Q14919
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