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DRAP1 Produkte

(DR1-Associated Protein 1 (Negative Cofactor 2 Alpha) (DRAP1))
Transcriptional repression is a general mechanism for regulating transcriptional initiation in organisms ranging from yeast to humans. Accurate initiation of transcription from eukaryotic protein-encoding genes requires the assembly of a large multiprotein complex consisting of RNA polymerase II and general transcription factors such as TFIIA, TFIIB, and TFIID. DR1 is a repressor that interacts with the TATA-binding protein (TBP) of TFIID and prevents the formation of an active transcription complex by precluding the entry of TFIIA and/or TFIIB into the preinitiation complex. The protein encoded by this gene is a corepressor of transcription that interacts with DR1 to enhance DR1-mediated repression. The interaction between this corepressor and DR1 is required for corepressor function and appears to stabilize the TBP-DR1-DNA complex. [provided by RefSeq, Jul 2008].

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Ausgewählte DRAP1 Kategorien

DRAP1 Antikörper

High quality antibodies with extensive validation data.

DRAP1 ELISA Kits

Reliable ELISA kits for a wide range of species.

DRAP1 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene DRAP1 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation ELISA, WB
Validierungen
  • (2)
Kat. Nr. ABIN564619
Menge 50 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB
Validierungen
  • (1)
Kat. Nr. ABIN1538849
Menge 400 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB
Validierungen
  • (1)
Kat. Nr. ABIN7266844
Menge 100 μL
Datenblatt Datenblatt

Empfohlene DRAP1 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method
Validierungen
Kat. Nr. ABIN1130683
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method
Validierungen
Kat. Nr. ABIN1130684
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Rat
Analytical Method
Validierungen
Kat. Nr. ABIN1130685
Menge 96 tests
Datenblatt Datenblatt

Empfohlene DRAP1 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1352006
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1352008
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Insect Cells
Validierungen
  • (1)
Kat. Nr. ABIN3084282
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren DRAP1 Produkten

Burkard, Planyavsky, Kaupe, Breitwieser, Bürckstümmer, Bennett, Superti-Furga, Colinge: "Initial characterization of the human central proteome." in: BMC systems biology, Vol. 5, pp. 17, (2011) (PubMed).

Klejman, Pereira, van Zeeburg, Gilfillan, Meisterernst, Timmers: "NC2alpha interacts with BTAF1 and stimulates its ATP-dependent association with TATA-binding protein." in: Molecular and cellular biology, Vol. 24, Issue 22, pp. 10072-82, (2004) (PubMed).

Gerhard, Wagner, Feingold, Shenmen, Grouse, Schuler, Klein, Old, Rasooly, Good, Guyer, Peck, Derge, Lipman, Collins, Jang, Sherry, Feolo, Misquitta, Lee, Rotmistrovsky, Greenhut, Schaefer, Buetow et al.: "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). ..." in: Genome research, Vol. 14, Issue 10B, pp. 2121-7, (2004) (PubMed).

Goppelt, Stelzer, Lottspeich, Meisterernst: "A mechanism for repression of class II gene transcription through specific binding of NC2 to TBP-promoter complexes via heterodimeric histone fold domains." in: The EMBO journal, Vol. 15, Issue 12, pp. 3105-16, (1996) (PubMed).

Mermelstein, Yeung, Cao, Inostroza, Erdjument-Bromage, Eagelson, Landsman, Levitt, Tempst, Reinberg: "Requirement of a corepressor for Dr1-mediated repression of transcription." in: Genes & development, Vol. 10, Issue 8, pp. 1033-48, (1996) (PubMed).

Synonyme und alternative Namen zu DRAP1

DR1-associated protein 1 (negative cofactor 2 alpha) (drap1), DR1 associated protein 1 (DRAP1), Dr1 associated protein 1 (negative cofactor 2 alpha) (Drap1), Dr1 associated protein 1 (Drap1), 2310074H19Rik, DRAP1, fb26e10, NC2-alpha, wu:fb26e10, zgc:56003, zgc:77337

Bezeichner auf Proteinebene für DRAP1

  • dr1-associated corepressor
  • DR1-associated protein 1 (negative cofactor 2 alpha)
  • NC2-alpha
  • dr1-associated protein 1
  • negative co-factor 2-alpha
  • negative cofactor 2 alpha
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