This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This CLEC6A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 137-163 amino acids from the C-terminal region of human CLEC6A.
CLEC4N antikoerper, CLECSF10 antikoerper, CLEC6A antikoerper, C-type lectin domain containing 6A antikoerper, C-type lectin domain family 6, member A antikoerper, CLEC6A antikoerper, Clec6a antikoerper
Hintergrund
Like dectin-1 (CLEC7A, MIM 606264), CLEC6A, or dectin-2, is a type II membrane receptor with an extracellular C-type lectin-like domain fold. However, unlike dectin-1, dectin-2 lacks an immunoreceptor tyrosine-based activation motif (ITAM) in its cytoplasmic domain (Kanazawa et al., 2004 [PubMed 15175046]).