RIMS2 Antikörper (Middle Region)

Produktnummer ABIN1449962

Produktdetails anti-RIMS2 Antikörper

Target: RIMS2 (Regulating Synaptic Membrane Exocytosis 2 (RIMS2))

Bindungsspezifität: Middle Region

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RIMS2 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: 17 amino acid synthetic peptide near the center of Human RIM2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu RIMS2

Target: RIMS2 (Regulating Synaptic Membrane Exocytosis 2 (RIMS2))

Andere Bezeichnung: RIMS2 (RIMS2 Produkte)

Synonyme: OBOE antikoerper, RAB3IP3 antikoerper, RIM2 antikoerper, 2810036I15Rik antikoerper, AW048769 antikoerper, Rab3ip2 antikoerper, Rim2(+40A) antikoerper, Rim2(+44A) antikoerper, Rim2(+4A) antikoerper, Serg2 antikoerper, Syt3-rs antikoerper, mKIAA0751 antikoerper, Nim2 antikoerper, Rim2 antikoerper, RIMS2 antikoerper, MGC159469 antikoerper, rims2 antikoerper, zgc:73064 antikoerper, drs antikoerper, drsp antikoerper, mema antikoerper, np-a antikoerper, pinin antikoerper, pnn antikoerper, pnn-a antikoerper, pnn-b antikoerper, sdk3 antikoerper, regulating synaptic membrane exocytosis 2 antikoerper, regulating synaptic membrane exocytosis 2a antikoerper, pinin, desmosome associated protein S homeolog antikoerper, RIMS2 antikoerper, Rims2 antikoerper, rims2a antikoerper, pnn.S antikoerper

Hintergrund: Rab3-interacting molecules (RIMs) are synaptic proteins necessary for neuronal transmission and plasticity. Rim1 and Rim2 proteins are expressed in overlapping but distinct patterns throughout the brain. While the ablation of either gene was not lethal in mice, the deletion of both resulted in postnatal mortality. This lethality is due to a defect in neurotransmitter release, synapses without RIM proteins can still release neurotransmitters but are unable to do so in response to normal Ca2+ triggers. Like Rim1, Rim2 is thought to be an effector protein for Rab3, binding to Rab3 on synaptic vesicles in a GTP-dependent manner.Synonyms: KIAA0751, RAB3IP3, RIM 2, RIM2, Rab-3-interacting molecule 2, Rab-3-interacting protein 3, Regulating synaptic membrane exocytosis protein 2

Gen-ID: 9699

NCBI Accession: NP_001093587

Pathways: Hormone Transport, Synaptic Vesicle Exocytosis