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RIMS2 Antikörper (Center)

RIMS2 Reaktivität: Human, Ratte, Maus WB, IHC (p), EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN500608
  • Target Alle RIMS2 Antikörper anzeigen
    RIMS2 (Regulating Synaptic Membrane Exocytosis 2 (RIMS2))
    Bindungsspezifität
    • 5
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Center
    Reaktivität
    • 27
    • 14
    • 4
    • 1
    • 1
    • 1
    Human, Ratte, Maus
    Wirt
    • 22
    • 10
    • 1
    Kaninchen
    Klonalität
    • 25
    • 8
    Polyklonal
    Konjugat
    • 15
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser RIMS2 Antikörper ist unkonjugiert
    Applikation
    • 15
    • 10
    • 9
    • 6
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Spezifität
    This antibody detects Rim2. Rim2 is known to exist in multiple isoforms, this antibody should recognize most of them. It is predicted to have no cross-reactivity to other Rim proteins.
    Kreuzreaktivität (Details)
    Species reactivity (tested):Human, mouse, rat
    Aufreinigung
    Peptide affinity chromatography
    Immunogen
    Rim2 antibody was raised against a 17 amino acid peptide near the center of the human Rim2.
    Isotyp
    IgG
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    Discover our top product RIMS2 Primärantikörper
  • Applikationshinweise
    ELISA. Western blot: 0.5 - 1 μg/mL. Immunohistochemistry on paraffin sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    PBS containing 0.02 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • Target
    RIMS2 (Regulating Synaptic Membrane Exocytosis 2 (RIMS2))
    Andere Bezeichnung
    RIMS2 (RIMS2 Produkte)
    Synonyme
    OBOE antikoerper, RAB3IP3 antikoerper, RIM2 antikoerper, 2810036I15Rik antikoerper, AW048769 antikoerper, Rab3ip2 antikoerper, Rim2(+40A) antikoerper, Rim2(+44A) antikoerper, Rim2(+4A) antikoerper, Serg2 antikoerper, Syt3-rs antikoerper, mKIAA0751 antikoerper, Nim2 antikoerper, Rim2 antikoerper, RIMS2 antikoerper, MGC159469 antikoerper, rims2 antikoerper, zgc:73064 antikoerper, drs antikoerper, drsp antikoerper, mema antikoerper, np-a antikoerper, pinin antikoerper, pnn antikoerper, pnn-a antikoerper, pnn-b antikoerper, sdk3 antikoerper, regulating synaptic membrane exocytosis 2 antikoerper, regulating synaptic membrane exocytosis 2a antikoerper, pinin, desmosome associated protein S homeolog antikoerper, RIMS2 antikoerper, Rims2 antikoerper, rims2a antikoerper, pnn.S antikoerper
    Hintergrund
    Rab3-interacting molecules (RIMs) are synaptic proteins necessary for neuronal transmission and plasticity. Rim1 and Rim2 proteins are expressed in overlapping but distinct patterns throughout the brain. While the ablation of either gene was not lethal in mice, the deletion of both resulted in postnatal mortality. This lethality is due to a defect in neurotransmitter release, synapses without RIM proteins can still release neurotransmitters but are unable to do so in response to normal Ca2+ triggers. Like Rim1, Rim 2 is thought to be an effector protein for Rab3, binding to Rab3 on synaptic vesicles in a GTP-dependent manner.Synonyms: KIAA0751, RAB3IP3, RIM 2, RIM2, Rab-3-interacting molecule 2, Rab-3-interacting protein 3, Regulating synaptic membrane exocytosis protein 2
    Gen-ID
    9699
    NCBI Accession
    NP_001093587
    UniProt
    Q9UQ26
    Pathways
    Hormone Transport, Synaptic Vesicle Exocytosis
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