HPTP antikoerper, HPTPD antikoerper, HPTPDELTA antikoerper, PTPD antikoerper, RPTPDELTA antikoerper, 1110002J03Rik antikoerper, 3000002J10Rik antikoerper, B230219D21Rik antikoerper, R-PTP-delta antikoerper, ptprd antikoerper, zgc:165626 antikoerper, ptpdelta antikoerper, rptpdelta antikoerper, xptp-d antikoerper, protein tyrosine phosphatase, receptor type D antikoerper, protein tyrosine phosphatase, receptor type, D antikoerper, receptor-type tyrosine-protein phosphatase delta antikoerper, protein tyrosine phosphatase, receptor type, D, b antikoerper, protein tyrosine phosphatase, receptor type D S homeolog antikoerper, PTPRD antikoerper, Ptprd antikoerper, LOC100155429 antikoerper, ptprdb antikoerper, ptprd.S antikoerper
Hintergrund
PTPRD (Protein tyrosine phosphatase receptor type D) is a member of the protein tyrosine phosphatase (PTP) family that plays diverse roles during development including cell growth, differentiation, mitotic cycle and oncogenic transformation. PTPRD contains an extracellular region, a single transmembrane segment and two tandem intracytoplasmic catalytic domains. The extracellular region of PTPRD is composed of three Ig-like and eight fibronectin type III-like domains (1,3). PTPRD interacts with PPFIA1-3 and is a tumor suppressor on chromosome 9p that is involved in the development of glioblastoma multiforme (GBMs) and multiple human cancers.Synonyms: Protein-tyrosine phosphatase delta, R-PTP-delta, Receptor-type tyrosine-protein phosphatase delta