PTPRD Antikörper (N-Term)

Produktnummer ABIN6991696

Produktdetails anti-PTPRD Antikörper

Target: PTPRD (Protein tyrosine Phosphatase, Receptor Type, D (PTPRD))

Bindungsspezifität: N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PTPRD Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Spezifität: PTPRD antibody is human specific. At least three alternatively spliced transcript variants encoding distinct isoforms have been observed. PTPRD cleavage products are often observed in vivo

Aufreinigung: PTPRD Antibody is affinity chromatography purified via peptide column.

Immunogen: PTPRD antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human PTPRD. The immunogen is located within the first 50 amino acids of PTPRD.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: PTPRD antibody can be used for detection of PTPRD by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PTPRD Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: PTPRD antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu PTPRD

Target: PTPRD (Protein tyrosine Phosphatase, Receptor Type, D (PTPRD))

Andere Bezeichnung: PTPRD (PTPRD Produkte)

Synonyme: HPTP antikoerper, HPTPD antikoerper, HPTPDELTA antikoerper, PTPD antikoerper, RPTPDELTA antikoerper, 1110002J03Rik antikoerper, 3000002J10Rik antikoerper, B230219D21Rik antikoerper, R-PTP-delta antikoerper, ptprd antikoerper, zgc:165626 antikoerper, ptpdelta antikoerper, rptpdelta antikoerper, xptp-d antikoerper, protein tyrosine phosphatase, receptor type D antikoerper, protein tyrosine phosphatase, receptor type, D antikoerper, receptor-type tyrosine-protein phosphatase delta antikoerper, protein tyrosine phosphatase, receptor type, D, b antikoerper, protein tyrosine phosphatase, receptor type D S homeolog antikoerper, PTPRD antikoerper, Ptprd antikoerper, LOC100155429 antikoerper, ptprdb antikoerper, ptprd.S antikoerper

Hintergrund: PTPRD Antibody: PTPRD (Protein tyrosine phosphatase receptor type D) is a member of the protein tyrosine phosphatase (PTP) family that plays diverse roles during development including cell growth, differentiation, mitotic cycle and oncogenic transformation. PTPRD contains an extracellular region, a single transmembrane segment and two tandem intracytoplasmic catalytic domains. The extracellular region of PTPRD is composed of three Ig-like and eight fibronectin type III-like domains (1,3). PTPRD interacts with PPFIA1-3 and is a tumor suppressor on chromosome 9p that is involved in the development of glioblastoma multiforme (GBMs) and multiple human cancers.

Molekulargewicht: Predicted: 165, 210 kDa (130 kDa for cleavage product)

Observed: 130 kDa

Gen-ID: 5789

NCBI Accession: NP_569075

UniProt: P23468

Pathways: Synaptic Membrane