Glypican 3 Antikörper (Middle Region)
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- Target Alle Glypican 3 (GPC3) Antikörper anzeigen
- Glypican 3 (GPC3)
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Bindungsspezifität
- AA 345-370, Middle Region
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Glypican 3 Antikörper ist unkonjugiert
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Applikation
- Immunofluorescence (IF), Enzyme Immunoassay (EIA)
- Spezifität
- This antibody recognizes Human and Mouse Glypican 3 (GPC3). Other species not tested.
- Aufreinigung
- Protein G Column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
- Immunogen
- KLH conjugated synthetic peptide selected from the center region of Human GPC3 (aa 345-370)
- Isotyp
- Ig Fraction
- Top Product
- Discover our top product GPC3 Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.25 mg/mL
- Buffer
- PBS containing 0.09 % (W/V) Sodium Azide as preservative
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- Target
- Glypican 3 (GPC3)
- Andere Bezeichnung
- Glypican-3 / GPC3 (GPC3 Produkte)
- Synonyme
- GPC3 antikoerper, sgb antikoerper, dgsx antikoerper, sdys antikoerper, sgbs antikoerper, oci-5 antikoerper, sgbs1 antikoerper, DGSX antikoerper, GTR2-2 antikoerper, MXR7 antikoerper, OCI-5 antikoerper, SDYS antikoerper, SGB antikoerper, SGBS antikoerper, SGBS1 antikoerper, Glypican-3 antikoerper, glypican 3 antikoerper, gpc3 antikoerper, GPC3 antikoerper, Gpc3 antikoerper
- Hintergrund
- GPC3 is a cell surface proteoglycan that bears heparan sulfate. This protein may be involved in the suppression/modulation of growth in the predominantly mesodermal tissues and organs, and may play a role in the modulation of IGF2 interactions with its receptor and thereby modulate its function. Members of the glypican-related integral membrane proteoglycan family contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol (GPI) linkage. These proteins may play a role in the control of cell division, growth regulation, and tumor predisposition. Deletion mutations in GPC3 are the cause of Simpson-Golabi-Behmel syndrome (SGBS), also known as Simpson dysmorphia syndrome (SDYS). SGBS is a condition characterized by pre- and postnatal overgrowth (gigantism) with visceral and skeletal anomalies.Synonyms: GTR2-2, Intestinal protein OCI-5, MXR7, OCI5
- Gen-ID
- 2719, 9606
- UniProt
- P51654
- Pathways
- Glycosaminoglycan Metabolic Process
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