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P-Selectin Antikörper (APC)
SELP
Reaktivität: Human, Primate
FACS
Wirt: Maus
Monoclonal
AK4
APC
Produktnummer ABIN1449147
Produktdetails anti-P-Selectin Antikörper (APC)
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Target
Alle P-Selectin (SELP) Antikörper anzeigen
P-Selectin (SELP)
(Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP))
Reaktivität
Alle Reaktivitäten für P-Selectin Antikörper
Human, Primate
Wirt
Alle Wirte für P-Selectin Antikörper
Maus
Klonalität
Alle Klonalitäten für P-Selectin Antikörper
Monoklonal
Konjugat
Alle Konjugate für P-Selectin Antikörper
Dieser P-Selectin Antikörper ist konjugiert mit APC
Applikation
Alle Applikationen für P-Selectin Antikörper
Flow Cytometry (FACS)
Kreuzreaktivität (Details)
Species reactivity (tested):Human, Primates
Immunogen
Human platelets
Klon
AK4
Isotyp
IgG1
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Alternativen
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anti-Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP) (AA 701-768) antibody
SELP
Reaktivität: Human, Maus, Ratte, Schwein
WB, FACS, ELISA, IHC (fro), IHC (p), IF (cc), IF (p)
Wirt: Kaninchen
Polyclonal
unconjugated
Anwendungsinformationen
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Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Buffer
Phosphate buffered saline (PBS), 15 mM sodium azide, 0.2 % (w/v) high-grade protease free Bovine Serum Albumin (BSA)
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
DO NOT FREEZE! This products is photosensitive and should be protected from light.
Lagerung
4 °C
Informationen zur Lagerung
Store undiluted at 2-8 °C.
Details zu P-Selectin
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Target
P-Selectin (SELP)
(Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP))
Andere Bezeichnung
CD62P / P-Selectin (SELP Produkte )
Synonyme
PSELECT antikoerper, CD62 antikoerper, CD62P antikoerper, GMP140 antikoerper, GRMP antikoerper, LECAM3 antikoerper, PADGEM antikoerper, PSEL antikoerper, GMP-140 antikoerper, Grmp antikoerper, selectin P antikoerper, selectin, platelet antikoerper, Selp antikoerper, SELP antikoerper
Hintergrund
CD62P (P-selectin) is an adhesion glycoprotein that is expressed on platelets and endothelial cells upon their activation. Interaction between CD62P and its mucin-like ligand PSGL-1 (P-selectin glycoprotein ligand-1) expressed on the microvilli of most leukocytes supports leukocyte rolling along postkapillary venules at the earliest time of inflammation. Both CD62P and PSGL-1 are extended glycoproteins that form homodimers. CD62P dimerization is probably mediated through interactions of the transmembrane domains and stabilizes leukocyte tethering and rolling, probably by increasing rebinding within a bond cluster.Synonyms: CD62 antigen-like family member P, GMP-140, GMRP, GRMP, Granule membrane protein 140, LECAM3, Leukocyte-endothelial cell adhesion molecule 3, PADGEM, SELP
Gen-ID
6403
NCBI Accession
NP_002996
UniProt
P16109
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