KCNAB2 Antikörper (AA 251-350) (HRP)

Produktnummer ABIN1413530

Der Kaninchen-Polyklonal Anti-KCNAB2-Antikörper wurde für ELISA, IHC (p) und IHC (fro) validiert. Er ist geeignet zum Nachweis von KCNAB2 in Proben aus Ratte. }

Kurzübersicht für KCNAB2 Antikörper (AA 251-350) (HRP) (ABIN1413530)

Target: KCNAB2 (Potassium Voltage-Gated Channel, Shaker-Related Subfamily, beta Member 2 (KCNAB2))

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KCNAB2 Antikörper ist konjugiert mit HRP

Applikation: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-KCNAB2 Antikörper (HRP)

Bindungsspezifität: AA 251-350

Kreuzreaktivität: Ratte

Homologie: Human,Mouse,Dog,Cow,Sheep,Pig,Rabbit,Zebrafish

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human KCNA2B/Kv beta 2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu KCNAB2

Target: KCNAB2 (Potassium Voltage-Gated Channel, Shaker-Related Subfamily, beta Member 2 (KCNAB2))

Andere Bezeichnung: KCNA2B/Kv beta 2

Hintergrund:

Synonyms: AKR6A5, HKv beta 2, HKvbeta 2, HKvbeta2.1, HKvbeta2.2, K+ channel subunit beta 2, K+ channel beta 2 subunit, KCNA2B, KCNAB 2, KCNAB2, KCNK2, Kv Beta 2, Kvbeta2, MGC117289, Potassium channel shaker chain beta 2, Potassium voltage gated channel shaker related subfamily, Potassium voltage gated channel shaker related subfamily beta member 2, Voltage gated potassium channel beta 2 subunit, Voltage gated potassium channel subunit beta 2,

Background: Voltage-gated K+ channels in the plasma membrane control the repolarization and the frequency of action potentials in neurons, muscles, and other excitable cells. The KV gene family encodes more than 30 genes that comprise the subunits of the K+ channels, and they vary in their gating and permeation properties, subcellular distribution, and expression patterns. Functional KV channels assemble as tetramers consisting of pore-forming a-subunits (KV), which include the KV1, KV2, KV3, and KV4 proteins, and accessory or KV-subunits that modify the gating properties of the coexpressed KV subunits. Differences exist in the patterns of trafficking, biosynthetic processing, and surface expression of the major KV1 subunits (KV1.1, KV1.2, and KV1.4) expressed in rat and human brain, suggesting that the individual protein subunits are highly regulated to control for the assembly and formation of functional neuronal channels. KV beta.2 can also be designated KCNAB2, KKv beta2.1 or AKR6A5.