KCNAB2 Antikörper

Produktnummer ABIN7117722

Produktdetails anti-KCNAB2 Antikörper

Target: KCNAB2 (Potassium Voltage-Gated Channel, Shaker-Related Subfamily, beta Member 2 (KCNAB2))

Reaktivität: Ratte, Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KCNAB2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen: potassium voltage-gated channel, shaker-related subfamily, beta member 2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Haltbarkeit: 12 months

Details zu KCNAB2

Target: KCNAB2 (Potassium Voltage-Gated Channel, Shaker-Related Subfamily, beta Member 2 (KCNAB2))

Andere Bezeichnung: KCNAB2 (KCNAB2 Produkte)

Synonyme: kcnab2 antikoerper, KCNAB2 antikoerper, DKFZp459E056 antikoerper, akr6a5 antikoerper, kcna2b antikoerper, kvb-a antikoerper, kvb2 antikoerper, kvbeta2 antikoerper, kvbeta2.1 antikoerper, kvbeta2.2 antikoerper, AKR6A5 antikoerper, HKvbeta2 antikoerper, HKvbeta2.1 antikoerper, HKvbeta2.2 antikoerper, KCNA2B antikoerper, KV-BETA-2 antikoerper, Kvbeta2.1 antikoerper, F5 antikoerper, I2rf5 antikoerper, Kcnb3 antikoerper, kv-beta-2 antikoerper, potassium channel, voltage gated subfamily A regulatory beta subunit 1 antikoerper, potassium voltage-gated channel subfamily A regulatory beta subunit 2 antikoerper, potassium voltage-gated channel, shaker-related subfamily, beta member 2 a antikoerper, potassium channel, voltage gated subfamily A regulatory beta subunit 2 L homeolog antikoerper, voltage-gated potassium channel subunit beta-2 antikoerper, potassium voltage-gated channel, shaker-related subfamily, beta member 2 antikoerper, kcnab1 antikoerper, KCNAB2 antikoerper, kcnab2a antikoerper, kcnab2.L antikoerper, LOC397248 antikoerper, Kcnab2 antikoerper

Hintergrund: Synonyms:KCNA2B, KCNK2 Background:Cytoplasmic potassium channel subunit that modulates the characteristics of the channel-forming alpha-subunits(PubMed:7649300, PubMed:11825900). Contributes to the regulation of nerve signaling, and prevents neuronal hyperexcitability(By similarity). Promotes expression of the pore-forming alpha subunits at the cell membrane, and thereby increases channel activity(By similarity). Promotes potassium channel closure via a mechanism that does not involve physical obstruction of the channel pore(PubMed:7649300, PubMed:11825900). Promotes KCNA4 channel closure(PubMed:7649300, PubMed:11825900). Modulates the functional properties of KCNA5(By similarity). Enhances KCNB2 channel activity(By similarity). Binds NADPH and has NADPH-dependent aldoketoreductase activity(By similarity). Has broad substrate specificity and can catalyze the reduction of methylglyoxal, 9,10-phenanthrenequinone, prostaglandin J2, 4-nitrobenzaldehyde, 4-nitroacetophenone and 4-oxo-trans-2-nonenal(in vitro)(By similarity).

Molekulargewicht: 38kd

Gen-ID: 8514

UniProt: Q13303