KCNJ1 Antikörper (pSer44) (HRP)

Produktnummer ABIN1413494

Der Kaninchen Polyklonal anti-KCNJ1 Antikörper wird verwendet zum Nachweis von KCNJ1 in Proben von Human. Er wurde validiert für ELISA, IHC (p) und IHC (fro).

Kurzübersicht für KCNJ1 Antikörper (pSer44) (HRP) (ABIN1413494)

Target: KCNJ1 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 1 (KCNJ1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KCNJ1 Antikörper ist konjugiert mit HRP

Applikation: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-KCNJ1 Antikörper (HRP)

Bindungsspezifität: pSer44

Homologie: Human,Mouse,Rat,Dog,Sheep,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human KCNJ1 around the phosphorylation site of Ser44

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu KCNJ1

Target: KCNJ1 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 1 (KCNJ1))

Andere Bezeichnung: KCNJ1

Hintergrund:

Synonyms: KCNJ1 phospho S44, p-KCNJ1 phospho S44, KCNJ1 phospho Ser44, p-KCNJ1 Ser44, p-ROM-Kphospho S44, KCNJ1 phospho S25, p-KCNJ1 phospho S25, KCNJ1 phospho Ser25, p-KCNJ1 Ser25, p-ROM-Kphospho S25, ROM K, ROM-K, inwardly rectying subfamily J member 1, ATP regulated potassium channel ROM K, ATP sensitive inward rectier potassium channel 1, ATP-regulated potassium channel ROM-K, ATP-sensitive inward rectier potassium channel 1, Inward rectier K+ channel Kir1.1, inwardly rectying K+ channel, IRK1_HUMAN, KCNJ 1, KCNJ, Kcnj1, Kir 1.1, Kir1.1, Potassium channel, Potassium channel inwardly rectying subfamily J member 1, potassium inwardly-rectying channel J1, ROMK 1, ROMK 2, ROMK, ROMK1, ROMK2.

Background: Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. It is activated by internal ATP and probably plays an important role in potassium homeostasis. The encoded protein has a greater tendency to allow potassium to flow into a cell rather than out of a cell. Mutations in this gene have been associated with antenatal Bartter syndrome, which is characterized by salt wasting, hypokalemic alkalosis, hypercalciuria, and low blood pressure. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].