PPP2R5C Antikörper (AA 390-435) (HRP)

Produktnummer ABIN1412414

Der Kaninchen Polyklonal anti-PPP2R5C Antikörper wird verwendet zum Nachweis von PPP2R5C in Proben von Ratte und Maus. Er wurde validiert für WB, ELISA, IHC (fro) und IHC (p).

Kurzübersicht für PPP2R5C Antikörper (AA 390-435) (HRP) (ABIN1412414)

Target: PPP2R5C (Protein Phosphatase 2, Regulatory Subunit B', gamma (PPP2R5C))

Reaktivität: Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PPP2R5C Antikörper ist konjugiert mit HRP

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-PPP2R5C Antikörper (HRP)

Bindungsspezifität: AA 390-435

Kreuzreaktivität: Maus, Ratte

Homologie: Human,Dog,Cow,Sheep,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PPP2R5C

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu PPP2R5C

Target: PPP2R5C (Protein Phosphatase 2, Regulatory Subunit B', gamma (PPP2R5C))

Andere Bezeichnung: PPP2R5C

Hintergrund:

Synonyms: 2A5G_HUMAN, B' alpha regulatory subunit, B56G, KIAA0044, MGC23064, PP2A B subunit B' gamma isoform, PP2A B subunit B56 gamma isoform, PP2A B subunit isoform B''-gamma, PP2A B subunit isoform B56-gamma, PP2A B subunit isoform PR61-gamma, PP2A B subunit isoform R5-gamma, PP2A B subunit PR61 gamma isoform, PP2A B subunit R5 gamma isoform, Ppp2r5c, PR61G, Protein phosphatase 2 regulatory subunit B B56 gamma isoform, Protein phosphatase 2 regulatory subunit B' gamma, Renal carcinoma antigen NY REN 29, Renal carcinoma antigen NY-REN-29, Serine/threonine protein phosphatase 2A 56 kDa regulatory subunit gamma isoform, Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform, 2A5G_HUMAN.

Background: In eukaryotes, the phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions, including division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the protein phosphatases. In general, the protein phosphatase (PP) holoenzyme is a trimeric complex composed of a regulatory subunit, a variable subunit, and a catalytic subunit. Four major families of protein phosphatase catalytic subunits have been identified, designated PP1, PP2A, PP2B (calcineurin) and PP2C. An additional protein phosphatase catalytic subunit, PPX (also known as PP4) is a putative member of a novel PP family. The PP2A family comprises subfamily members PP2A Alpha and PP2A Beta. The PP2A catalytic subunit associates with a variety of regulatory subunits. Regulatory subunits include PP2A-A-Alpha and -A-Beta, PP2A-B-Alpha and -B-Beta, PP2A-C-Alpha and -C-Beta, PP2A-B56-Alpha, -B56-Beta, -B56-gamma and -B56-Delta.

Pathways: PI3K-Akt Signalweg