Influenza Nucleoprotein Antikörper (Influenza A Virus (A/Russia:St.Petersburg/8/2006)) (AA 71-170) (Biotin)
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- Target Alle Influenza Nucleoprotein (NP) Antikörper anzeigen
- Influenza Nucleoprotein (NP)
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Bindungsspezifität
- AA 71-170
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Reaktivität
- Influenza A Virus, Virus
- Virus Strain
- A/Russia:St.Petersburg/8/2006
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Biotin
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Applikation
- Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Kreuzreaktivität
- Virus
- Kreuzreaktivität (Details)
- Influenza A virus
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from Influenza A virus (strain A/Russia:St.Petersburg/8/2006 H1N1) Nucleoprotein
- Isotyp
- IgG
- Top Product
- Discover our top product NP Primärantikörper
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- Applikationshinweise
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WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C for 12 months.
- Haltbarkeit
- 12 months
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IN OVO AND IN VITRO SUSCEPTIBILITY OF AMERICAN ALLIGATORS (ALLIGATOR MISSISSIPPIENSIS) TO AVIAN INFLUENZA VIRUS INFECTION." in: Journal of wildlife diseases, (2014) (PubMed).
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IN OVO AND IN VITRO SUSCEPTIBILITY OF AMERICAN ALLIGATORS (ALLIGATOR MISSISSIPPIENSIS) TO AVIAN INFLUENZA VIRUS INFECTION." in: Journal of wildlife diseases, (2014) (PubMed).
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- Target
- Influenza Nucleoprotein (NP)
- Andere Bezeichnung
- Influenza A virus Nucleoprotein (NP Produkte)
- Synonyme
- nucleoprotein antikoerper, NP antikoerper
- Substanzklasse
- Influenza Protein
- Hintergrund
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Synonyms: Nucleoprotein, NP, Nucleocapsid protein, Protein N, Influenza A virus H1N1, H3N2 Nucleoprotein, H9N2 Nucleoprotein, H2N2 Nucleoprotein, H3N8 Nucleoprotein, H7N7 Nucleoprotein, H5N1 Nucleoprotein.
Background: Encapsidates the negative strand viral RNA, protecting it from nucleases. The encapsidated genomic RNA is termed the ribonucleoprotein (RNP) and serves as template for transcription and replication. The RNP needs to be localized in the nucleus to start an infectious cycle, but is too large to diffuse through the nuclear pore complex. NP comprises at least 2 nuclear localization signals and is responsible of the active RNP import into the nucleus through the cellular importin alpha/beta pathway. Later in the infection, nucleus export of RNP are mediated through viral proteins NEP interacting with M1 which binds nucleoproteins. It is possible that the nucleoprotein binds directly exportin-1 (XPO1) and plays an active role in RNP nuclear export. M1 interaction with RNP seems to hide nucleoprotein's nuclear localization signals. Soon after a virion infects a new cell, M1 dissociates from the RNP under acidification of the virion driven by M2 protein. Dissociation of M1 from RNP unmask nucleoprotein's nuclear localization signals, targeting the RNP to the nucleus.
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