Metabotropic Glutamate Receptor 1 Antikörper (AA 151-250) (Alexa Fluor 555)
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- Target Alle Metabotropic Glutamate Receptor 1 (GRM1) Antikörper anzeigen
- Metabotropic Glutamate Receptor 1 (GRM1) (Glutamate Receptor, Metabotropic 1 (GRM1))
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Bindungsspezifität
- AA 151-250
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Reaktivität
- Maus, Zebrafisch (Danio rerio)
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Metabotropic Glutamate Receptor 1 Antikörper ist konjugiert mit Alexa Fluor 555
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Applikation
- Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
- Kreuzreaktivität
- Maus, Zebrafisch (Danio rerio)
- Homologie
- Human,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human MGLUR1A/Metabotropic Glutamate Receptor 1a
- Isotyp
- IgG
- Top Product
- Discover our top product GRM1 Primärantikörper
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- Applikationshinweise
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- Metabotropic Glutamate Receptor 1 (GRM1) (Glutamate Receptor, Metabotropic 1 (GRM1))
- Andere Bezeichnung
- MGLUR1A/Metabotropic Glutamate Receptor 1a (GRM1 Produkte)
- Synonyme
- fj39d05 antikoerper, wu:fj39d05 antikoerper, si:ch211-51a19.1 antikoerper, Glura antikoerper, mGlutR antikoerper, GB18621 antikoerper, GPRC1A antikoerper, MGLU1 antikoerper, MGLUR1 antikoerper, SCAR13 antikoerper, 4930455H15Rik antikoerper, ENSMUSG00000075319 antikoerper, Gm10828 antikoerper, Gprc1a antikoerper, mGluR1 antikoerper, nmf373 antikoerper, rcw antikoerper, wobl antikoerper, glutamate metabotropic receptor 1 antikoerper, glutamate receptor, metabotropic 1a antikoerper, metabotropic glutamate receptor 1 antikoerper, glutamate receptor, metabotropic 1 antikoerper, GRM1 antikoerper, grm1a antikoerper, mGlutR1 antikoerper, Grm1 antikoerper
- Hintergrund
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Synonyms: G protein coupled receptor family C group 1 member A, Glutamate receptor metabotropic 1 alpha, Glutamate receptor metabotropic 1, GPRC1A, GRM 1, GRM1 alpha, GRM1, GRM1A, Human metabotropic glutamate receptor 1 alpha mRNA complete cds, Metabotropic glutamate receptor 1 alpha, Metabotropic glutamate receptor 1, mGlu1, MGLUR1, MGLUR1A, mGluR1alpha.
Background: L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Alternative splice variants of the GRM1 gene have been described but their full-length nature has not been determined.
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