Metabotropic Glutamate Receptor 1 Antikörper (AA 387-486)

Produktnummer ABIN5611175

Dieser Maus Monoklonal Antikörper detektiert spezifisch Metabotropic Glutamate Receptor 1 in ELISA. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für Metabotropic Glutamate Receptor 1 Antikörper (AA 387-486) (ABIN5611175)

Target: Metabotropic Glutamate Receptor 1 (GRM1) (Glutamate Receptor, Metabotropic 1 (GRM1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Metabotropic Glutamate Receptor 1 Antikörper ist unkonjugiert

Applikation: ELISA

Klon: 5E12D8

Produktdetails anti-Metabotropic Glutamate Receptor 1 Antikörper

Bindungsspezifität: AA 387-486

Verwendungszweck: GRM1 Antibody

Aufreinigung: Purified antibody

Immunogen: Purified recombinant fragment of human GRM1 (AA: 387-486) expressed in E. Coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1/10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Details zu Metabotropic Glutamate Receptor 1

Target: Metabotropic Glutamate Receptor 1 (GRM1) (Glutamate Receptor, Metabotropic 1 (GRM1))

Andere Bezeichnung: GRM1

Hintergrund: This gene encodes a metabotropic glutamate receptor that functions by activating phospholipase C. L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The canonical alpha isoform of the encoded protein is a disulfide-linked homodimer whose activity is mediated by a G-protein-coupled phosphatidylinositol-calcium second messenger system. This gene may be associated with many disease states, including schizophrenia, bipolar disorder, depression, and breast cancer. Alternative splicing results in multiple transcript variants encoding different isoforms.

Molekulargewicht: 132.4 kDa

Gen-ID: 2911