Metabotropic Glutamate Receptor 1 Antikörper (AA 920-1140)

Produktnummer ABIN6141420

Der Kaninchen Polyklonal anti-Metabotropic Glutamate Receptor 1 Antikörper wird verwendet zum Nachweis von Metabotropic Glutamate Receptor 1 in Proben von Human. Er wurde validiert für WB.

Kurzübersicht für Metabotropic Glutamate Receptor 1 Antikörper (AA 920-1140) (ABIN6141420)

Target: Metabotropic Glutamate Receptor 1 (GRM1) (Glutamate Receptor, Metabotropic 1 (GRM1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Metabotropic Glutamate Receptor 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Metabotropic Glutamate Receptor 1 Antikörper

Bindungsspezifität: AA 920-1140

Sequenz: NETACNQTAV IKPLTKSYQG SGKSLTFSDT STKTLYNVEE EEDAQPIRFS PPGSPSMVVH RRVPSAATTP PLPSHLTAEE TPLFLAEPAL PKGLPPPLQQ QQQPPPQQKS LMDQLQGVVS NFSTAIPDFH AVLAGPGGPG NGLRSLYPPP PPPQHLQMLP LQLSTFGEEL VSPPADDDDD SERFKLLQEY VYEHEREGNT EEDELEEEEE DLQAASKLTP D

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 920-1140 of human GRM1 (NP_000829.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu Metabotropic Glutamate Receptor 1

Target: Metabotropic Glutamate Receptor 1 (GRM1) (Glutamate Receptor, Metabotropic 1 (GRM1))

Andere Bezeichnung: GRM1

Hintergrund: This gene encodes a metabotropic glutamate receptor that functions by activating phospholipase C. L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The canonical alpha isoform of the encoded protein is a disulfide-linked homodimer whose activity is mediated by a G-protein-coupled phosphatidylinositol-calcium second messenger system. This gene may be associated with many disease states, including schizophrenia, bipolar disorder, depression, and breast cancer. Alternative splicing results in multiple transcript variants encoding different isoforms.,GRM1,GPRC1A,MGLU1,MGLUR1,PPP1R85,SCAR13,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Neuroscience,Neurodegenerative Diseases,GRM1

Molekulargewicht: 101 kDa/132 kDa

Gen-ID: 2911

UniProt: Q13255