ELF3 Antikörper (AA 201-300) (Alexa Fluor 488)

Produktnummer ABIN1390324

Produktdetails anti-ELF3 Antikörper (Alexa Fluor 488)

Target: ELF3 (E74-Like Factor 3 (Ets Domain Transcription Factor, Epithelial-Specific) (ELF3))

Bindungsspezifität: AA 201-300

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ELF3 Antikörper ist konjugiert mit Alexa Fluor 488

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Human

Homologie: Mouse,Rat,Dog,Cow,Sheep

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ESE1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu ELF3

Target: ELF3 (E74-Like Factor 3 (Ets Domain Transcription Factor, Epithelial-Specific) (ELF3))

Andere Bezeichnung: ESE1/ELF3 (ELF3 Produkte)

Synonyme: ert antikoerper, esx antikoerper, epr-1 antikoerper, ese-1 antikoerper, ESE-1 antikoerper, ESX antikoerper, jen antikoerper, EPR-1 antikoerper, ERT antikoerper, E74 like ETS transcription factor 3 antikoerper, E74-like factor 3 antikoerper, elf3 antikoerper, Elf3 antikoerper, ELF3 antikoerper

Hintergrund:

Synonyms: E74 like factor 3, E74 like factor 3 ets domain transcription factor, E74 like factor 3 ets domain transcription factor epithelial specic, E74 like factor 3 ETS domain transcription factor serine box epithelial specic, E74-like factor 3, Elf3, ELF3_HUMAN, Epithelial restricted with serine box, Epithelial-restricted with serine box, Epithelium restricted Ets protein ESX, Epithelium specic Ets factor 1, Epithelium specic Ets transcription factor 1, Epithelium-restricted Ets protein ESX, Epithelium-specic Ets transcription factor 1, EPR 1, EPR1, ERT, ESE-1, ESX, Ets domain transcription factor serine box, Ets domain transcription factor serine box epithelial specic, Ets transcription factor, ETS-related transcription factor Elf-3, jen, MGC139318.

Background: ESE-1, a member of the Ets family of transcription factors, critically regulates epithelial cell differentiation and mediates vascular inflammation. ESE-1 is strongly expressed in vascular endothelium and smooth muscle cells where it is induced in response to inflammatory cytokines and lipopolysaccharides, interacts with NF-KappaB to induce nitric oxide synthase, and is induced during terminal differentiation of epidermal and primary keratinocytes. In addition, ESE-1 is upregulated upon differentiation of corneal epithelium and interacts with Sp1 and AP-1 proteins to induce squamous differentiation marker expression in bronchial epithelial cells.