FNDC5 Antikörper (AA 81-143)

Produktnummer ABIN1387505

Produktdetails anti-FNDC5 Antikörper

Target: FNDC5 (Fibronectin Type III Domain Containing 5 (FNDC5))

Bindungsspezifität: AA 81-143

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FNDC5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Kreuzreaktivität: Human, Maus, Ratte

Homologie: Dog,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human FNDC5 Irisin

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-FNDC5 Antikörper (ABIN1387505)

Gao, Li, Li, Huang, Liu, Chen: "Effects and Molecular Mechanism of GST-Irisin on Lipolysis and Autocrine Function in 3T3-L1 Adipocytes." in: PLoS ONE, Vol. 11, Issue 1, pp. e0147480, (2016) (PubMed).

Park, Kim, Choi, Heo, Park: "New role of irisin in hepatocytes: The protective effect of hepatic steatosis in vitro." in: Cellular signalling, Vol. 27, Issue 9, pp. 1831-9, (2015) (PubMed).

Details zu FNDC5

Target: FNDC5 (Fibronectin Type III Domain Containing 5 (FNDC5))

Andere Bezeichnung: FNDC5 (FNDC5 Produkte)

Synonyme: FRCP2 antikoerper, irisin antikoerper, 1500001L03Rik antikoerper, AI836596 antikoerper, C87088 antikoerper, PeP antikoerper, Pxp antikoerper, fndc5 antikoerper, si:dkey-264p5.1 antikoerper, zgc:158684 antikoerper, fibronectin type III domain containing 5 antikoerper, fibronectin type III domain containing 5b antikoerper, FNDC5 antikoerper, Fndc5 antikoerper, fndc5b antikoerper

Hintergrund:

Synonyms: FRCP2, irisin, Fibronectin type III domain-containing protein 5, Fibronectin type III repeat-containing protein 2, FNDC5

Background: Irisin: Contrary to mouse, may not be involved in the beneficial effects of muscular exercise, nor in the induction of browning of human white adipose tissue.

Gen-ID: 252995

UniProt: Q8NAU1

Pathways: Hormone Activity, Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation