GRIK1 Antikörper (AA 181-280)

Produktnummer ABIN1387480

Produktdetails anti-GRIK1 Antikörper

Target: GRIK1 (Glutamate Receptor, Ionotropic, Kainate 1 (GRIK1))

Bindungsspezifität: AA 181-280

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GRIK1 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GRIK1/GLR5

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu GRIK1

Target: GRIK1 (Glutamate Receptor, Ionotropic, Kainate 1 (GRIK1))

Andere Bezeichnung: GRIK1/GLR5 (GRIK1 Produkte)

Synonyme: GRIK1 antikoerper, grik1 antikoerper, fv36b03 antikoerper, wu:fv36b03 antikoerper, EAA3 antikoerper, EEA3 antikoerper, GLR5 antikoerper, GLUR5 antikoerper, GluK1 antikoerper, A830007B11Rik antikoerper, D16Ium24 antikoerper, D16Ium24e antikoerper, GluK5 antikoerper, Glur-5 antikoerper, Glur5 antikoerper, Glurbeta1 antikoerper, GluR5 antikoerper, glutamate ionotropic receptor kainate type subunit 1 antikoerper, glutamate receptor, ionotropic, kainate 1a antikoerper, glutamate receptor, ionotropic, kainate 1 antikoerper, GRIK1 antikoerper, grik1a antikoerper, Grik1 antikoerper

Hintergrund:

Synonyms: GluR-5/6/7, EAA3, EEA3, Excitatory amino acid receptor 3, GLR5, GluR-5, GluR5, GluR6, GluR7, Glutamate receptor 5, Glutamate receptor, Glutamate receptor ionotropic kainate 1, GRIK1, GRIK1_HUMAN, Human glutamate receptor GLUR5, ionotropic kainate 1, OTTHUMP00000096569.

Background: Glutamate receptors mediate most excitatory neurotransmission in the brain and play an important role in neural plasticity, neural development and neurodegeneration. Ionotropic glutamate receptors are categorized into NMDA receptors and kainate/AMPA receptors, both of which contain glutamate-gated, cation-specific ion channels. Kainate/AMPA receptors are co-localized with NMDA receptors in many synapses and consist of seven structurally related subunits designated GluR-1 to -7. The kainate/AMPA receptors are primarily responsible for the fast excitatory neuro-transmission by glutamate, whereas the NMDA receptors are functionally characterized by a slow kinetic and a high permeability for Ca2+ ions. The NMDA receptors consist of five subunits: epsilion 1, 2, 3, 4 and one zeta subunit. The zeta subunit is expressed throughout the brainstem, whereas the four epsilon subunits display limited distribution.

Pathways: Synaptic Membrane, Regulation of long-term Neuronal Synaptic Plasticity