PSMB7 Antikörper (pSer214)

Produktnummer ABIN1387051

Produktdetails anti-PSMB7 Antikörper

Target: PSMB7 (Proteasome (Prosome, Macropain) Subunit, beta Type, 7 (PSMB7))

Bindungsspezifität: pSer214

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PSMB7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human Proteasome 20S beta 7 around the phosphorylation site of Ser214

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu PSMB7

Target: PSMB7 (Proteasome (Prosome, Macropain) Subunit, beta Type, 7 (PSMB7))

Abstract: PSMB7 Produkte

Synonyme: DDBDRAFT_0185624 antikoerper, DDBDRAFT_0232933 antikoerper, DDB_0185624 antikoerper, DDB_0232933 antikoerper, AU020723 antikoerper, MC14 antikoerper, Z antikoerper, 20S proteasome subunit beta-7 antikoerper, proteasome (prosome, macropain) subunit, beta type, 7 S homeolog antikoerper, proteasome subunit beta 7 antikoerper, proteasome (prosome, macropain) subunit, beta type, 7 antikoerper, proteasome (prosome, macropain) subunit, beta type 7 antikoerper, psmB7 antikoerper, psmb7.S antikoerper, PSMB7 antikoerper, Psmb7 antikoerper

Hintergrund:

Synonyms: Proteasome 20S beta 7 phospho S214, Proteasome 20S beta 7 phospho Ser214, p-Proteasome 20S beta 7 S214, p-Proteasome 20S beta 7 Ser214,20S Proteasome _7, Macropain chain Z, Multicatalytic endopeptidase complex chain Z, Proteasome prosome macropain subunit beta type 7, Proteasome beta 7 subunit, Proteasome catalytic subunit 2, Proteasome subunit alpha, Proteasome subunit beta 7, Proteasome subunit beta type-7, Proteasome subunit Z, PSB7_HUMAN, PSMB7, PUP1.

Background: The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH . The proteasome has an ATP-dependent proteolytic activity. This unit is responsible of the trypsin-like activity.The proteasome represents a large protein complex that exists inside all eukaryotes and archaea, and in some bacteria. The main function of proteasomes is to degrade unnecessary or damaged proteins by proteolysis. The most common form of the proteasome, known as the 26S Proteasome, contains one 20S Proteasome core particle structure and two 19S regulatory caps. The 20S Proteasome core is hollow and forms an enclosed cavity, where proteins are degraded, as well as openings at the two ends to allow the target protein to enter. The 20S Proteasome core particle contains many subunits, depending on the organism.

Gen-ID: 5688

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA