GRIA4 Antikörper (AA 351-450)

Produktnummer ABIN1386653

Produktdetails anti-GRIA4 Antikörper

Target: GRIA4 (Glutamate Receptor, Ionotropic, AMPA 4 (GRIA4))

Bindungsspezifität: AA 351-450

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GRIA4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)

Kreuzreaktivität: Maus

Homologie: Human,Rat,Dog,Cow,Sheep,Horse,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GluA4/Ionotropic Glutamate receptor 4

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu GRIA4

Target: GRIA4 (Glutamate Receptor, Ionotropic, AMPA 4 (GRIA4))

Andere Bezeichnung: GluA4/Ionotropic Glutamate receptor 4 (GRIA4 Produkte)

Synonyme: GLUR4 antikoerper, GLUR4C antikoerper, GLURD antikoerper, GluA4 antikoerper, GluR4 antikoerper, GluR4d antikoerper, GLUR4/D antikoerper, glur4 antikoerper, GluR-D antikoerper, Glur-4 antikoerper, Glur4 antikoerper, Gluralpha4 antikoerper, spkw1 antikoerper, DKFZp459P0616 antikoerper, glur4a antikoerper, gria4 antikoerper, iGluR4 antikoerper, ZfGluR4b antikoerper, fj46g06 antikoerper, glur4b antikoerper, wu:fj46g06 antikoerper, glutamate ionotropic receptor AMPA type subunit 4 antikoerper, glutamate receptor, ionotropic, AMPA 4 antikoerper, glutamate receptor, ionotropic, AMPA4 (alpha 4) antikoerper, glutamate receptor, ionotropic, AMPA 4a antikoerper, glutamate receptor, ionotropic, AMPA 4b antikoerper, GRIA4 antikoerper, gria4 antikoerper, Gria4 antikoerper, gria4a antikoerper, gria4b antikoerper

Hintergrund:

Synonyms: AMPA 4, AMPA selective glutamate receptor 4, AMPA-selective glutamate receptor 4, AMPA4, GluA 4, GluA4, GluR 4, GluR D, GluR-4, GluR-D, GLUR4, GLUR4C, GLURD, Glutamate receptor 4, Glutamate receptor ionotrophic AMPA 4, Glutamate receptor ionotropic, GRIA 4, GRIA4, GRIA4_HUMAN.

Background: Glutamate receptors mediate most excitatory neurotransmission in the brain and play an important role in neural plasticity, neural development and neurodegeneration. Ionotropic glutamate receptors are categorized into NMDA receptors and kainate/AMPA receptors, both of which contain glutamate-gated, cation-specific ion channels. Kainate/AMPA receptors are co-localized with NMDA receptors in many synapses and consist of seven structurally related subunits designated GluR-1 to -7. The kainate/AMPA receptors are primarily responsible for the fast excitatory neuro-transmission by glutamate, whereas the NMDA receptors are functionally characterized by a slow kinetic and a high permeability for Ca2+ ions. The NMDA receptors consist of five subunits: epsilion 1, 2, 3, 4 and one zeta subunit. The zeta subunit is expressed throughout the brainstem, whereas the four epsilon subunits display limited distribution.

Gen-ID: 2893

Pathways: PI3K-Akt Signalweg