CD80 Antikörper
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- Target Alle CD80 Antikörper anzeigen
- CD80
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Reaktivität
- Maus
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Wirt
- Ratte
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Klonalität
- Monoklonal
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Konjugat
- Dieser CD80 Antikörper ist unkonjugiert
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Applikation
- Flow Cytometry (FACS)
- Spezifität
- Mouse CD80 (B7-1)
- Aufreinigung
- Purified
- Isotyp
- IgG2a
- Top Product
- Discover our top product CD80 Primärantikörper
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 0.2 mg/ml
- Buffer
- Purified Ig buffered in PBS, 0.1% NaN and EIA grade BSA to bring total protein concentration to 4-5 mg/ml.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C
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- Target
- CD80
- Andere Bezeichnung
- CD80 (CD80 Produkte)
- Synonyme
- B7 antikoerper, B7-1 antikoerper, B7.1 antikoerper, BB1 antikoerper, CD28LG antikoerper, CD28LG1 antikoerper, LAB7 antikoerper, B71 antikoerper, Cd28l antikoerper, Ly-53 antikoerper, Ly53 antikoerper, MIC17 antikoerper, TSA1 antikoerper, CD80 molecule antikoerper, Cd80 molecule antikoerper, CD80 antigen antikoerper, CD80 antikoerper, Cd80 antikoerper
- Hintergrund
- ABIN134038reacts with the murine CD80 (B7-1) molecule. This member of the Ig superfamily, along with CD86 (B7-2), participates in T cell co- stimulation via interactions with CD28 and CTLA-4. CD80 is constitutively ex- pressed on dendritic cells, monocytes, and peritoneal macrophages and it is in- ducible on B cells by various means, including activation by LPS, IL-4, and the cross-linking of surface Ig. Expression of CD80 is greatly enhanced on splenic B cells following activation by LPS, with peak expression occurring between 48 and 72 hours. It has been reported that activation of purified B cells with LPS can induce CD80 expression in as few as 18 hours.
- Pathways
- T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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