LAMP2 Antikörper

Produktnummer ABIN133965

Produktdetails anti-LAMP2 Antikörper

Target: LAMP2 (Lysosomal-Associated Membrane Protein 2 (LAMP2))

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser LAMP2 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS)

Spezifität: Mouse MAC-3

Aufreinigung: Purified

Immunogen: Immunoadsorbent purified mouse macrophage glycoprotein fraction. . Fusion Partner: NS-1 . Donor: Rat spleen

Isotyp: IgG1

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/ml

Lagerung: 4 °C

Referenzen für anti-LAMP2 Antikörper (ABIN133965)

Lindsey, Ma, Flynn, Winniford, Hall, DeLeon-Pennell: "Identifying the molecular and cellular signature of cardiac dilation following myocardial infarction." in: Biochimica et biophysica acta. Molecular basis of disease, Vol. 1865, Issue 7, pp. 1845-1852, (2020) (PubMed).

Jung, Ma, Iyer, DeLeon-Pennell, Yabluchanskiy, Garrett, Lindsey: "IL-10 improves cardiac remodeling after myocardial infarction by stimulating M2 macrophage polarization and fibroblast activation." in: Basic research in cardiology, Vol. 112, Issue 3, pp. 33, (2018) (PubMed).

Kain, Ingle, Colas, Dalli, Prabhu, Serhan, Joshi, Halade: "Resolvin D1 activates the inflammation resolving response at splenic and ventricular site following myocardial infarction leading to improved ventricular function." in: Journal of molecular and cellular cardiology, Vol. 84, pp. 24-35, (2016) (PubMed).

Iyer, Patterson, Zouein, Ma, Dive, de Castro Brás, Lindsey: "Early matrix metalloproteinase-12 inhibition worsens post-myocardial infarction cardiac dysfunction by delaying inflammation resolution." in: International journal of cardiology, Vol. 185, pp. 198-208, (2016) (PubMed).

Yan, Zhou, Hu, Pham: "Suppression of experimental arthritis through AMP-activated protein kinase activation and autophagy modulation." in: Journal of rheumatic diseases and treatment, Vol. 1, Issue 1, pp. 5, (2015) (PubMed).

DeLeon-Pennell, de Castro Brás, Iyer, Bratton, Jin, Ripplinger, Lindsey: "P. gingivalis lipopolysaccharide intensifies inflammation post-myocardial infarction through matrix metalloproteinase-9." in: Journal of molecular and cellular cardiology, Vol. 76, pp. 218-26, (2015) (PubMed).

Zhou, Yan, Hu, Springer, Yang, Wickline, Pan, Lanza, Pham: "Fumagillin prodrug nanotherapy suppresses macrophage inflammatory response via endothelial nitric oxide." in: ACS nano, Vol. 8, Issue 7, pp. 7305-17, (2015) (PubMed).

Deleon-Pennell, de Castro Brás, Lindsey: "Circulating Porphyromonas gingivalis lipopolysaccharide resets cardiac homeostasis in mice through a matrix metalloproteinase-9-dependent mechanism." in: Physiological reports, Vol. 1, Issue 5, pp. e00079, (2014) (PubMed).

Heaberlin, Ma, Zhang, Ahuja, Lindsey, Halade: "Obese and diabetic KKAy mice show increased mortality but improved cardiac function following myocardial infarction." in: Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology, Vol. 22, Issue 6, pp. 481-7, (2014) (PubMed).

Zamilpa, Ibarra, de Castro Brás, Ramirez, Nguyen, Halade, Zhang, Dai, Dayah, Chiao, Lowell, Ahuja, DArmiento, Jin, Lindsey: "Transgenic overexpression of matrix metalloproteinase-9 in macrophages attenuates the inflammatory response and improves left ventricular function post-myocardial infarction." in: Journal of molecular and cellular cardiology, Vol. 53, Issue 5, pp. 599-608, (2013) (PubMed).

Ma, Chiao, Zhang, Manicone, Jin, Lindsey: "Matrix metalloproteinase-28 deletion amplifies inflammatory and extracellular matrix responses to cardiac aging." in: Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada, Vol. 18, Issue 1, pp. 81-90, (2012) (PubMed).

Chiao, Dai, Zhang, Lin, Lopez, Ahuja, Chou, Lindsey, Jin: "Multi-analyte profiling reveals matrix metalloproteinase-9 and monocyte chemotactic protein-1 as plasma biomarkers of cardiac aging." in: Circulation. Cardiovascular genetics, Vol. 4, Issue 4, pp. 455-62, (2012) (PubMed).

Details zu LAMP2

Target: LAMP2 (Lysosomal-Associated Membrane Protein 2 (LAMP2))

Andere Bezeichnung: MAC-3 (LAMP2 Produkte)

Synonyme: CD107b antikoerper, LAMP-2 antikoerper, LAMPB antikoerper, LGP110 antikoerper, Lamp-2 antikoerper, Lamp-2a antikoerper, Lamp-2b antikoerper, Lamp-2c antikoerper, Mac3 antikoerper, cd107b antikoerper, lamp-2 antikoerper, lampb antikoerper, LAMP2 antikoerper, lamp2 antikoerper, DKFZp459J126 antikoerper, LGP-B antikoerper, sb:cb587 antikoerper, wu:fb14a06 antikoerper, zgc:103532 antikoerper, lysosomal associated membrane protein 2 antikoerper, lysosomal-associated membrane protein 2 antikoerper, lysosomal-associated membrane protein 2 S homeolog antikoerper, lysosomal membrane glycoprotein 2 antikoerper, LAMP2 antikoerper, Lamp2 antikoerper, lamp2.S antikoerper, lamp2 antikoerper

Hintergrund: Anti-mouse MAC-3 monoclonal antibody recognizes the MAC-3 antigen which is found on macrophages and some nonlymphoid tissues, but not on lymphocytes. It is a glycoprotein showing a broad band in SDS-PAGE, and is synthesized by macrophages (molecular weight 92-110,000 daltons, depending on the origin of macrophages). It reacts with peritoneal exudate macrophages where the exudate is provoked by thioglycollate, protease peptone, L. monocytogenes, lipopolysaccharide and concanavalin A. It does not react with thymocytes, spleen, lymph node or bone marrow cells in immunofluorescent flow cytometry. MAC-3 is a general marker for macrophages and can be used to distinguish these cells from lymphocytes. MAC-3 is differentiated from MAC-1 and MAC-2 antigens by its M (average)110,000 and by cell distribution.

Pathways: Autophagie