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CD3 epsilon Antikörper (FITC)

CD3E Reaktivität: Maus FACS Wirt: Hamster Monoclonal FITC

Produktnummer ABIN133683

Datenblatt (PDF)

Target Alle CD3 epsilon (CD3E) Antikörper anzeigen

CD3 epsilon (CD3E)
Reaktivität
202

148

44

37

18

8

8

8

7

4

4

4

4

3

3

3

3

3

3

1

1

1

1

1
Maus
Wirt
123

105

36

24

16

10

1

1
Hamster
Klonalität
206

104

6
Monoklonal
Konjugat
120

29

27

18

14

6

6

6

5

4

4

4

4

4

4

4

3

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Dieser CD3 epsilon Antikörper ist konjugiert mit FITC
Applikation
232

135

85

83

67

66

32

27

22

17

14

13

13

13

8

6

4

4

3

3

3

3

2

1

1

1

1

1

1

1

1

1
Flow Cytometry (FACS)

Spezifität

Mouse CD3

Immunogen

H-2Kb sp . Fusion Partner: Murine myeloma cell line SP2/0 . Donor: BALB/c

Isotyp

IgG

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CD3E Reaktivität: Human FACS, WB, IHC, ELISA, Coat, StM Wirt: Maus Monoclonal C3e-1931 unconjugated

anti-CD3 epsilon (CD3E) (AA 156-168), (Cytoplasmic Domain) antibody
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anti-CD3 epsilon (CD3E) (C-Term) antibody
CD3E Reaktivität: Human, Maus, Ratte WB, IHC, IF, ELISA, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-CD3 epsilon (CD3E) (C-Term) antibody
CD3E Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated

anti-CD3 epsilon (CD3E) (AA 25-207) antibody
CD3E Reaktivität: Human WB, IHC, IP Wirt: Kaninchen Polyclonal unconjugated

anti-CD3 epsilon (CD3E) (AA 28-185) antibody
CD3E Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated

Beschränkungen

Nur für Forschungszwecke einsetzbar
Konzentration

1µg/10 cells

Lagerung

4 °C
Target

CD3 epsilon (CD3E)

Andere Bezeichnung

CD3e (CD3E Produkte)

Synonyme

cd3e antikoerper, CD3E antikoerper, t3e antikoerper, tcre antikoerper, AI504783 antikoerper, CD3 antikoerper, CD3epsilon antikoerper, T3e antikoerper, T3E antikoerper, TCRE antikoerper, CD3e molecule antikoerper, CD3 antigen, epsilon polypeptide antikoerper, cd3e antikoerper, CD3E antikoerper, Cd3e antikoerper

Hintergrund

Anti-mouse T3 complex CD3 monoclonal antibody is specific for a 25 kDa protein component ( -T3) of the antigen specific T cell receptor on all mouse strains tested. The -T3 protein has been shown to be non-covalently associated with the cell surface heterodimer of the CD3 associated complex. This monoclonal antibody reacts with all mature T cells and can both activate and inhibit T cell function (1). This fact identifies -T3 as a cell surface protein involved in the transduction of activation signals. All peripheral T cells express this determinant, however, B cells and bone marrow cells have proven to be negative. Although the expression of this particular epitope on peripheral T cells is uniformly high, staining of thymocytes reveals distinct subpopulations of cells differing in the level of expression of this marker. This antibody will prove useful in studying the role of various components of the TCR complex in T cell activation and development, and will allow for the development of an animal model in which to investigate the immunoregulatory effects of in vivo administration of anti-CD3 antibodies, an area of obvious clinical

Pathways

T-Zell Rezeptor Signalweg, CXCR4-mediated Signaling Events, Ubiquitin Proteasome Pathway