C-JUN Antikörper

Produktnummer ABIN127313

Produktdetails anti-C-JUN Antikörper

Target: C-JUN (JUN) (Jun Proto-Oncogene (JUN))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser C-JUN Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: The antibody only recognizes c-Jun, and will not detect the endogenous levels of Jun B or Jun D.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Western blotting (0.5-2 μg/mL). Immunohistochemistry (20-40 μg/mL).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: PBS, pH 7.2, containing 50 % glycerol, 1 % BSA and 0.02 % thimerosal

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. For long-term storage, aliquot and freeze at -70 °C.

Details zu C-JUN

Target: C-JUN (JUN) (Jun Proto-Oncogene (JUN))

Andere Bezeichnung: AP-1 / C-Jun (JUN Produkte)

Synonyme: AP-1 antikoerper, AP1 antikoerper, c-Jun antikoerper, fj36h07 antikoerper, wu:fj36h07 antikoerper, zgc:65863 antikoerper, Junc antikoerper, c-jun antikoerper, CG2275 antikoerper, D-Jun antikoerper, D-jun antikoerper, D-jun/Jra antikoerper, DJUN antikoerper, DJun antikoerper, Djun antikoerper, Dmel\\CG2275 antikoerper, JRA antikoerper, JUN antikoerper, Jun antikoerper, V antikoerper, cJun antikoerper, d-JRA antikoerper, d-Jun antikoerper, d-jun antikoerper, dAP-1 antikoerper, dJRA antikoerper, dJUN antikoerper, dJra antikoerper, dJun antikoerper, djun antikoerper, dm-Jun antikoerper, jra antikoerper, jun antikoerper, l(2)46Ef antikoerper, l(2)IA109 antikoerper, l(2R)IA109 antikoerper, Jun proto-oncogene, AP-1 transcription factor subunit antikoerper, jun proto-oncogene S homeolog antikoerper, jun proto-oncogene antikoerper, Jun-related antigen antikoerper, jun proto-oncogene L homeolog antikoerper, JUN antikoerper, Jun antikoerper, jun.S antikoerper, jun antikoerper, Jra antikoerper, jun.L antikoerper

Hintergrund: Extracellular stimuli such as growth factors and UV irradiation stimulate phosphorylation of c-Jun at Ser63/73 and activate c-Jun dependent transcription. Mutation at Ser63/73 renders c-Jun nonresponsive to mitogenic and stress induced signaling pathways. JNK (c-jun N-terminal Kinase) binds to the N-terminal region of c-Jun and phosphorylates c-Jun at Ser63/73. The activity of JNK is stimulated by the same signals that activate c-Jun.Synonyms: Activator protein 1, Proto-oncogene c-jun, Transcription factor AP1, V-jun avian sarcoma virus 17 oncogene homolog, p39

Gen-ID: 3725

NCBI Accession: NP_002219

UniProt: P05412

Pathways: MAPK Signalweg, RTK Signalweg, WNT Signalweg, Fc-epsilon Rezeptor Signalübertragung, Activation of Innate immune Response, Myometrial Relaxation and Contraction, Skeletal Muscle Fiber Development, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Autophagie, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling, S100 Proteine