NR2E3 Antikörper

Produktnummer ABIN122365

Produktdetails anti-NR2E3 Antikörper

Target: NR2E3 (Nuclear Receptor Subfamily 2, Group E, Member 3 (NR2E3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NR2E3 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: Reacts with Photoreceptor-Specific Nuclear Receptor (PNR/NR2E3) (family: NHR, subfamily: NR2 Hepatocyte NF4-like). BLAST analysis of the peptide immunogen showed no homology with other human proteins.

Aufreinigung: Immunoaffinity Chromatography

Immunogen: Synthetic peptide - KLH conjugated

Anwendungsinformationen

Applikationshinweise: Immunohistochemistry with formalin fixed paraffin embedded tissues: 7 μg/mL Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100 °C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween (TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: This product was originally produced by MBL International.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS, 0.01 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-80 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -70 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu NR2E3

Target: NR2E3 (Nuclear Receptor Subfamily 2, Group E, Member 3 (NR2E3))

Andere Bezeichnung: NR2E3 (NR2E3 Produkte)

Synonyme: ESCS antikoerper, PNR antikoerper, RNR antikoerper, RP37 antikoerper, rd7 antikoerper, LOC100228348 antikoerper, A930035N01Rik antikoerper, wu:fj55b07 antikoerper, zgc:103631 antikoerper, nuclear receptor subfamily 2 group E member 3 antikoerper, nuclear receptor subfamily 2, group E, member 3 antikoerper, NR2E3 antikoerper, Nr2e3 antikoerper, nr2e3 antikoerper

Hintergrund: Photoreceptor-specific nuclear receptor (PNR), a NR2 Hepatocyte NF4-Like Receptor, has been suggested to affect cone cell proliferation in eye development. It has been shown to have a role in determining photoreceptor phenotype during human retinogenesis. In RD7 mice, a deletion in PNR results in hereditary retinal dysplasia and degeneration. A homozygous missense mutation in PNR has been linked to retinitis pigmentosa in Crypto-Jews of Belmonte. Two alternatively spliced isoforms have been documented. PNR is expressed in the retina. ESTs have been isolated from cancerous human lung, colon, and ovary, and from normal human eye.Synonyms: Nuclear receptor subfamily 2 group E member 3, PNR, Photoreceptor-specific nuclear receptor, RNR, Retina-specific nuclear receptor

Gen-ID: 10002

UniProt: Q9Y5X4

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway