PTH1R Antikörper

Produktnummer ABIN122361

Produktdetails anti-PTH1R Antikörper

Target: PTH1R (Parathyroid Hormone 1 Receptor (PTH1R))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PTH1R Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: The antibody reacts with Parathyroid Hormone Receptor Type 1 (PTHR1) (Family: GPCR, Subfamily: Parathyroid hormone)

Aufreinigung: Peptide immunogen affinity column

Immunogen: Synthetic peptide - KLH conjugated

Anwendungsinformationen

Applikationshinweise: Immunohistochemistry on paraffin embedded sections: 2-4 μg/mL Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100 °C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween (TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: This product was originally produced by MBL International.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS, pH 7.7 containing 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-80 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -70 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu PTH1R

Target: PTH1R (Parathyroid Hormone 1 Receptor (PTH1R))

Andere Bezeichnung: PTH Receptor 1 (PTH1R Produkte)

Synonyme: PFE antikoerper, PTHR antikoerper, PTHR1 antikoerper, PPR antikoerper, Pthr antikoerper, Pthr1 antikoerper, pthr1 antikoerper, zPTH1R antikoerper, PTHrel antikoerper, PTH1 antikoerper, PTH antikoerper, parathyroid hormone 1 receptor antikoerper, parathyroid hormone 1 receptor a antikoerper, PTH1R antikoerper, Pth1r antikoerper, pth1ra antikoerper

Hintergrund: PTHR1, a Parathyroid Hormone Receptor, mediates PTH-dependent regulation of mineral-ion homeostasis. It also mediates the paracrine action of PTHRP in endochondral bone formation. Mutations in this receptor are responsible for disorders of calcium and bone metabolism such as chondrodysplasia, hypercalcemia, and chronic renal failure. Three promoters, P1, P2, and P3, regulate the expression of PTHR. PTHR1 has been reported to be expressed in bone, breast, brain, colon, GI, kidney, liver, placenta, skin, umbilical cord, and uterus. ESTs have been isolated from B-cell/lung/testis, brain, breast, fetus, heart, heart / melanocyte / uterus, kidney, liver / spleen, lung, placenta, and testis librariesSynonyms: PTH/PTHrP type I receptor, PTH1R, PTHR, PTHR1, Parathyroid hormone 1 receptor, Parathyroid hormone/parathyroid hormone-related peptide receptor

Gen-ID: 5745

UniProt: Q03431

Pathways: Regulation of Carbohydrate Metabolic Process