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CD59 Antikörper

CD59 Reaktivität: Human, Schwein FACS, Func Wirt: Maus Monoclonal MEM-129 unconjugated
Produktnummer ABIN120694
  • Target Alle CD59 Antikörper anzeigen
    CD59
    Reaktivität
    • 135
    • 14
    • 9
    • 8
    • 5
    • 3
    • 2
    • 1
    • 1
    Human, Schwein
    Wirt
    • 88
    • 68
    • 6
    • 4
    Maus
    Klonalität
    • 94
    • 69
    • 1
    Monoklonal
    Konjugat
    • 77
    • 21
    • 16
    • 13
    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CD59 Antikörper ist unkonjugiert
    Applikation
    • 98
    • 69
    • 46
    • 40
    • 31
    • 26
    • 25
    • 15
    • 14
    • 14
    • 13
    • 12
    • 11
    • 11
    • 8
    • 3
    • 3
    • 3
    • 1
    • 1
    Flow Cytometry (FACS), Functional Studies (Func)
    Spezifität
    The antibody MEM-129 reacts with CD59 (Protectin).
    Aufreinigung
    Thiophilic Adsorption-Affinity Chromatography and Size-Exclusion Chromatography.
    Reinheit
    > 95 % (by SDS-PAGE).
    Immunogen
    Human peripheral blood lymphocytes
    Klon
    MEM-129
    Isotyp
    IgM
    Top Product
    Discover our top product CD59 Primärantikörper
  • Applikationshinweise
    Flow Cytometry. Functional Studies (The antibody activates T-cells).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1.0 mg/mL
    Buffer
    Phosphate buffered saline (PBS), preserved by filter sterilization, approx. pH 7.4
    Konservierungsmittel
    Azide free
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 4-8 °C. DO NOT FREEZE! Should this product contain a precipitate we recommend microcentrifugation before use.
    Shelf Life: one year from despatch.
    Haltbarkeit
    12 months
  • Target
    CD59
    Andere Bezeichnung
    CD59 (CD59 Produkte)
    Synonyme
    16.3A5 antikoerper, 1F5 antikoerper, EJ16 antikoerper, EJ30 antikoerper, EL32 antikoerper, G344 antikoerper, HRF-20 antikoerper, HRF20 antikoerper, MAC-IP antikoerper, MACIF antikoerper, MEM43 antikoerper, MIC11 antikoerper, MIN1 antikoerper, MIN2 antikoerper, MIN3 antikoerper, MIRL antikoerper, MSK21 antikoerper, p18-20 antikoerper, Cd59a antikoerper, Cd59b antikoerper, MACIP antikoerper, CD59 molecule (CD59 blood group) antikoerper, CD59 molecule antikoerper, CD59 antikoerper, Cd59 antikoerper
    Hintergrund
    CD59 (Protectin) is a small (18-20 kDa) GPI-anchored ubiquitously expressed inhibitor of the membrane attack complex (MAC). It is thus the key regulator that preserves the autologous cells from terminal effector mechanism of the complement cascade. CD59 associates with C5b-8 complex and thereby counteracts appropriate formation of cytolytic pore within the plasma membrane. CD59 is also an low-affinity ligand of human CD2 and causes T cell costimulation.Synonyms: 20 kDa homologous restriction factor, HRF-20, HRF20, MAC-IP, MAC-inhibitory protein, MACIF, MEM43 antigen, MIC11, MIN1, MIN2, MIN3, MIRL, MSK21, Membrane attack complex inhibition factor, Membrane inhibitor of reactive lysis, Protectin
    Gen-ID
    966
    UniProt
    P13987
    Pathways
    Komplementsystem
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