IL-2 Antikörper (PE)

Produktnummer ABIN119948

Produktdetails anti-IL-2 Antikörper (PE)

Target: IL-2 (IL2) (Interleukin 2 (IL2))

Reaktivität: Human, Affe

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser IL-2 Antikörper ist konjugiert mit PE

Applikation: Flow Cytometry (FACS)

Klon: MQ1-17H12

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Flow Cytometry: Neat - 1/10, Use 10 μL of the suggested working dilution to label 10^6 cells or 100 μL whole blood,Membrane permeabilisation is required for this application.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS containing 0.09 % Sodium Azide and 0.5 % Bovine Serum Albumin

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Dilute only prior to immediate use

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C. DO NOT FREEZE! Freezing alkaline phosphatase conjugates will result in a substantial loss of enzymatic activity.

Details zu IL-2

Target: IL-2 (IL2) (Interleukin 2 (IL2))

Andere Bezeichnung: Interleukin-2 / IL2 (IL2 Produkte)

Synonyme: IL2 antikoerper, IL-2 antikoerper, il2 antikoerper, TCGF antikoerper, lymphokine antikoerper, Il-2 antikoerper, POIL2 antikoerper, interleukin 2 antikoerper, interleukin-15 antikoerper, IL2 antikoerper, il2 antikoerper, LOC100303688 antikoerper, Il2 antikoerper

Hintergrund: Interleukin 2 (IL2) is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli. IL2 has been shown to have antitumor effects in some studies. This is probably mediated by cytotoxic effector cells.Synonyms: IL-2, T-cell growth factor, TCGF

Gen-ID: 9606

UniProt: P60568

Pathways: JAK-STAT Signalweg, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation