SLC3A2 Antikörper

Produktnummer ABIN118817

Produktdetails anti-SLC3A2 Antikörper

Target: SLC3A2 (Solute Carrier Family 3 (Activators of Dibasic and Neutral Amino Acid Transport), Member 2 (SLC3A2))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser SLC3A2 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Spezifität: This antibody reacts with the heavy chain of the CD98 Molecule. This antibody binds to all cell lines in culture and to activated Tcells. Note: The epitope is distinct from clone 44H7 (SM1173), but the same as recognised by 4F2.

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Affinity Chromatography on Protein G.

Immunogen: HOON pre-B leukaemia cell line. Spleen cells from immunised BALB/c mice were fused with cells of the SP2/0-Ag14 mouse myeloma cell line.

Klon: 44D7

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Flow Cytometry: Use 10 μL of 1/50-1/200 diluted antibody to label 10^6 cells in 100 μL. Immunohistochemistry on Frozen Sections. Immunoprecipitation.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu SLC3A2

Target: SLC3A2 (Solute Carrier Family 3 (Activators of Dibasic and Neutral Amino Acid Transport), Member 2 (SLC3A2))

Andere Bezeichnung: CD98 / SLC3A2 (SLC3A2 Produkte)

Synonyme: 4F2 antikoerper, 4F2HC antikoerper, 4T2HC antikoerper, CD98 antikoerper, CD98HC antikoerper, MDU1 antikoerper, NACAE antikoerper, Mdu1 antikoerper, MGC53951 antikoerper, slc3a2 antikoerper, MGC53965 antikoerper, SLC3A2 antikoerper, AI314110 antikoerper, Cd98 antikoerper, Ly-10 antikoerper, Ly-m10 antikoerper, Ly10 antikoerper, Mgp-2hc antikoerper, fc65h12 antikoerper, wu:fc65h12 antikoerper, id:ibd1327 antikoerper, sb:cb519 antikoerper, wu:fe14a07 antikoerper, wu:fq18d12 antikoerper, zgc:55813 antikoerper, solute carrier family 3 member 2 antikoerper, solute carrier family 3 (amino acid transporter heavy chain), member 2 L homeolog antikoerper, solute carrier family 3 (amino acid transporter heavy chain), member 2 S homeolog antikoerper, solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2 antikoerper, solute carrier family 3 (amino acid transporter heavy chain), member 2a antikoerper, solute carrier family 3 (amino acid transporter heavy chain), member 2b antikoerper, SLC3A2 antikoerper, Slc3a2 antikoerper, slc3a2.L antikoerper, slc3a2.S antikoerper, slc3a2a antikoerper, slc3a2b antikoerper

Hintergrund: CD98 is a type II transmembrane glycoprotein which associates with members of the L-type amino transporter family to form a heterodimeric complexCD98 constitutes the heavy chain of the complex and is required for the surface expression and basolateral localization of the amino acid transporter complex in polarized epithelial cells. The CD98 heavy chain also interacts with beta 1 integrins and regulates their activation through the cytoplasmic domains and transmembrane regions. Studies suggest that overexpression of CD98 may contribute to cell growth and survival by regulating integrin signalling, and therefore may play an important role in tumorigenesis. The tissue distribution of this antigen is broad. Monocytes express high levels of CD98 antigen. Peripheral blood T and B cells, as well as NK cells and granulocytes express low levels of CD98 antigen. Activation of T cells and NK cells leads to upregulation of this antigen.Synonyms: 4F2 cell-surface antigen heavy chain, 4F2 heavy chain antigen, 4F2hc, Lymphocyte activation antigen 4F2 large subunit, MDU1

Gen-ID: 6520

NCBI Accession: NP_001012680

UniProt: P08195