SLC3A2 Antikörper

Produktnummer ABIN94255

Produktdetails anti-SLC3A2 Antikörper

Target: SLC3A2 (Solute Carrier Family 3 (Activators of Dibasic and Neutral Amino Acid Transport), Member 2 (SLC3A2))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser SLC3A2 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: The antibody MEM-108 reacts with an extracellular epitope of CD98, a 125 kDa disulfide-linked heterodimer (80 kDa glycosylated heavy chain + 45 kDa non-glykosylated light chain). CD98 is expressed on T lymphocytes (upon activation) and activated NK cells, it is also present at low levels on B lymphocytes, NK cells, monocytes and platelets.

Kreuzreaktivität (Details): Human

Aufreinigung: Purified by protein-A affinity chromatography.

Reinheit: > 95 % (by SDS-PAGE)

Immunogen: RAJI human Burkitt's lymphoma cell line

Klon: MEM-108

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Flow cytometry: Recommended dilution: 4 μg/mL.
Immunohistochemistry (paraffin sections): Recommended dilution: 10 μg/mL, positive tissue: liver.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Do not freeze.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2-8°C. Do not freeze.

Details zu SLC3A2

Target: SLC3A2 (Solute Carrier Family 3 (Activators of Dibasic and Neutral Amino Acid Transport), Member 2 (SLC3A2))

Andere Bezeichnung: CD98 (SLC3A2 Produkte)

Synonyme: 4F2 antikoerper, 4F2HC antikoerper, 4T2HC antikoerper, CD98 antikoerper, CD98HC antikoerper, MDU1 antikoerper, NACAE antikoerper, Mdu1 antikoerper, MGC53951 antikoerper, slc3a2 antikoerper, MGC53965 antikoerper, SLC3A2 antikoerper, AI314110 antikoerper, Cd98 antikoerper, Ly-10 antikoerper, Ly-m10 antikoerper, Ly10 antikoerper, Mgp-2hc antikoerper, fc65h12 antikoerper, wu:fc65h12 antikoerper, id:ibd1327 antikoerper, sb:cb519 antikoerper, wu:fe14a07 antikoerper, wu:fq18d12 antikoerper, zgc:55813 antikoerper, solute carrier family 3 member 2 antikoerper, solute carrier family 3 (amino acid transporter heavy chain), member 2 L homeolog antikoerper, solute carrier family 3 (amino acid transporter heavy chain), member 2 S homeolog antikoerper, solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2 antikoerper, solute carrier family 3 (amino acid transporter heavy chain), member 2a antikoerper, solute carrier family 3 (amino acid transporter heavy chain), member 2b antikoerper, SLC3A2 antikoerper, Slc3a2 antikoerper, slc3a2.L antikoerper, slc3a2.S antikoerper, slc3a2a antikoerper, slc3a2b antikoerper

Hintergrund: Solute carrier family 7 member 5,CD98 (4F2) is a type II transmembrane glycoprotein which serves as the heavy chain of the heterodimeric amino acid transporters (HATs). CD98, linked to various light chains by disulfide bond, is responsible for cell surface expression and basolateral localization of this transporter complex in polarized epithelial cells and also interacts with beta1 integrins and increases their affinity for ligand. Besides its roles in amino acid transport, CD98 is thus involved in cell fusion and activation. It is implicated in regulation of cellular differentiation, growth and apoptosis.,4F2, MDU1, 4F2HC, 4T2HC, NACAE, SLC3A2

Gen-ID: 8140

UniProt: Q01650