IL-7 Antikörper (Biotin)

Produktnummer ABIN115888

Produktdetails anti-IL-7 Antikörper (Biotin)

Target: IL-7 (IL7) (Interleukin 7 (IL7))

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IL-7 Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Spezifität: This antibody reacts with Mouse Interleukin-7 (IL-7). Other species not tested.

Aufreinigung: Affinity Chromatography

Immunogen: Highly pure (>98%) E.ocli derived recombinant Mouse IL-7 (Cat.-No PA014).

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Restore in sterile PBS containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL.

Buffer: PBS, pH 7.2 without preservatives

Konservierungsmittel: Without preservative

Handhabung: Avoid repeated freezing and thawing. Centrifuge vial prior to opening!

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody at 2-8 °C for one month or at -20 °C for longer.

Details zu IL-7

Target: IL-7 (IL7) (Interleukin 7 (IL7))

Andere Bezeichnung: Interleukin-7 / IL7 (IL7 Produkte)

Synonyme: IL7 antikoerper, IL-7 antikoerper, A630026I06Rik antikoerper, Il-7 antikoerper, hlb368 antikoerper, interleukin 7 antikoerper, IL7 antikoerper, Il7 antikoerper

Hintergrund: Interleukin 7 (IL7) is a lymphoid cell growth factor that affects pre-B, pro-B, and early T cells. IL7 was previously known as pre-B cell growth factor and lymphopoietin 1. IL7 supports the growth of early B cells from long-term lymphoid bone marrow cultures. It is mitogenic to thymocytes and enhances the response of cells to other stimuli such as polyhydroxyalkanoate (PHA) and concanavalin A (ConA). IL7 stimulates the proliferation of CD4+/CD8+ cells. The proliferative response of thymocytes to IL7 is not affected by antibodies to the T cell growth factors such as IL2, IL4 and IL6, suggesting that IL7 is capable of stimulating T cell proliferation through a pathway independent of the known T cell growth factors. Mature T cells respond to IL7 and Con A, but not to IL7 alone. In myeloid lineage cells, IL7 upregulates the production of pro-inflammatory cytokines and stimulates the tumoricidal activity of monocytes/macrophages. IL7 is expressed by adherent stromal cells from various tissues.Synonyms: IL-7

Gen-ID: 16196

NCBI Accession: NP_032397

UniProt: P10168

Pathways: JAK-STAT Signalweg