PTPRJ Antikörper (AA 1-444) (PE)
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- Target Alle PTPRJ Antikörper anzeigen
- PTPRJ (Protein tyrosine Phosphatase, Receptor Type, J (PTPRJ))
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Bindungsspezifität
- AA 1-444
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser PTPRJ Antikörper ist konjugiert mit PE
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Applikation
- Flow Cytometry (FACS)
- Spezifität
- The mouse monoclonal antibody MEM-CD148/05 recognizes an extracellular epitope of CD148, a highly glycosylated up to 250 kDa receptor-like protein tyrosin phosphatase expressed mainly in lymphocytes, myeloid cells and epithelial cells.
- Kreuzreaktivität (Details)
- Human
- Aufreinigung
- Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
- Immunogen
- Human recombinant CD148 (amino acids 1-444)
- Klon
- MEM-CD148-05
- Isotyp
- IgG2b
- Top Product
- Discover our top product PTPRJ Primärantikörper
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- Applikationshinweise
- Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
- Kommentare
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The purified antibody is conjugated with R-Phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Rekonstitution
- No reconstitution is necessary.
- Buffer
- Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
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Do not freeze.
Avoid prolonged exposure to light. - Lagerung
- 4 °C
- Informationen zur Lagerung
- Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
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- Target
- PTPRJ (Protein tyrosine Phosphatase, Receptor Type, J (PTPRJ))
- Andere Bezeichnung
- CD148 (PTPRJ Produkte)
- Synonyme
- HAAP antikoerper, CD148 antikoerper, DEP1 antikoerper, HPTPeta antikoerper, R-PTP-ETA antikoerper, SCC1 antikoerper, AI450271 antikoerper, BET antikoerper, Byp antikoerper, DEP-1 antikoerper, PTPbeta2 antikoerper, Ptpb2 antikoerper, RPTPJ antikoerper, Scc-1 antikoerper, Scc1 antikoerper, PTPRJ antikoerper, acid phosphatase 1 antikoerper, protein tyrosine phosphatase, receptor type J antikoerper, protein tyrosine phosphatase, receptor type, J antikoerper, ACP1 antikoerper, PTPRJ antikoerper, Ptprj antikoerper, EUBREC_2762 antikoerper
- Hintergrund
- Protein tyrosine phosphatase receptor type J,CD148 (also known as HPTP-eta or DEP-1) is a transmembrane protein tyrosin phosphatase, containing eight fibronectin type III extracellular domains. This protein is known to inhibit transduction of mitogenic signals in non-hematopoietic cells (fibroblasts, epithelial cells), and signal transduction downstream of T cell receptor, however, it also augments immunoreceptor signaling in B cells and macrophages via dephosphorylating C-terminal tyrosine of Src-family tyrosine kinases. CD148 expression increases after in vitro activation of peripheral blood leucocytes. It can be also used as marker of the most mature human thymocytes, and leukemic cells corresponding to this stadium of thymocyte differentiation. In contrast, in mice the CD148 expression sharply drops through the double positive stage to the single positive thymocytes.,HPTP-eta, DEP-1, PTPRJ, DEP1, SCC1, HPTPeta, R-PTP-ETA
- Gen-ID
- 5795
- UniProt
- Q12913
- Pathways
- EGFR Signaling Pathway, Platelet-derived growth Factor Receptor Signaling
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