SPTA1 Antikörper

Produktnummer ABIN1109118

Produktdetails anti-SPTA1 Antikörper

Target: SPTA1 (Spectrin alpha 1, Erythrocytic (SPTA1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser SPTA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Spezifität: This antibody reacts to Spectrin (erythrocyte) (alpha / beta).

Aufreinigung: Affinity chromatography

Immunogen: Human erythrocyte spectrin

Klon: Spe 1-2

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Restore with 1.2 % sodium acetate or neutral PBS

Konzentration: 0,1 mg/mL

Buffer: 1.2 % sodium acetate, with 2 mg BSA and 0.01 mg sodium azide as preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Prior to reconstitution store at -20 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu SPTA1

Target: SPTA1 (Spectrin alpha 1, Erythrocytic (SPTA1))

Andere Bezeichnung: Spectrin alpha Chain (Erythrocyte) / SPTA1 (SPTA1 Produkte)

Synonyme: Spna1 antikoerper, AF093576 antikoerper, AI451697 antikoerper, Spna-1 antikoerper, ha antikoerper, ihj antikoerper, nmf4 antikoerper, sph antikoerper, EL2 antikoerper, HPP antikoerper, HS3 antikoerper, SPH3 antikoerper, SPTA antikoerper, spectrin, alpha, erythrocytic 1 antikoerper, spectrin alpha, erythrocytic 1 antikoerper, Spta1 antikoerper, SPTA1 antikoerper

Hintergrund: Spectrin, the predominant component of the membrane skeleton of the red cell, is essential in determining the properties of the membrane including its shape and deformability. It consists of 2 nonidentical subunits, alpha and beta. Spectrin is present in the red cell membrane in a tetrameric or possibly higher polymeric form through head-to-head self-association of heterodimers that are linked by actin polymers and protein 4.1 to form a 2-dimensional network. Non-erythroid spectrin gene is mapped to human chromosome 2.Spectrin mutations cause spinocerebellar ataxia type 5.Synonyms: Erythroid alpha-spectrin, SPTA

Gen-ID: 6708

NCBI Accession: NP_003117

UniProt: P02549

Pathways: Regulation of Actin Filament Polymerization