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SPTA1 Antikörper

SPTA1 Reaktivität: Human, Maus, Ratte IHC, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7256054
  • Target Alle SPTA1 Antikörper anzeigen
    SPTA1 (Spectrin alpha 1, Erythrocytic (SPTA1))
    Reaktivität
    • 24
    • 11
    • 3
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 17
    • 8
    Kaninchen
    Klonalität
    • 13
    • 12
    Polyklonal
    Konjugat
    • 18
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser SPTA1 Antikörper ist unkonjugiert
    Applikation
    • 16
    • 9
    • 8
    • 6
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    Immunohistochemistry (IHC), Immunofluorescence (IF)
    Produktmerkmale
    Polyclonal Antibody
    Aufreinigung
    Affinity purification
    Immunogen
    Recombinant fusion protein of human SPTA1 (NP_003117.2).
    Isotyp
    IgG
    Top Product
    Discover our top product SPTA1 Primärantikörper
  • Applikationshinweise
    IHC 1:50-1:200 IF 1:50-1:200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    SPTA1 (Spectrin alpha 1, Erythrocytic (SPTA1))
    Andere Bezeichnung
    SPTA1 (SPTA1 Produkte)
    Synonyme
    Spna1 antikoerper, AF093576 antikoerper, AI451697 antikoerper, Spna-1 antikoerper, ha antikoerper, ihj antikoerper, nmf4 antikoerper, sph antikoerper, EL2 antikoerper, HPP antikoerper, HS3 antikoerper, SPH3 antikoerper, SPTA antikoerper, spectrin, alpha, erythrocytic 1 antikoerper, spectrin alpha, erythrocytic 1 antikoerper, Spta1 antikoerper, SPTA1 antikoerper
    Hintergrund
    Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. It is a tetramer made up of alpha-beta dimers linked in a head-to-head arrangement. This gene is one member of a family of alpha-spectrin genes. The encoded protein is primarily composed of 22 spectrin repeats which are involved in dimer formation. It forms weaker tetramer interactions than non-erythrocytic alpha spectrin, which may increase the plasma membrane elasticity and deformability of red blood cells. Mutations in this gene result in a variety of hereditary red blood cell disorders, including elliptocytosis type 2, pyropoikilocytosis, and spherocytic hemolytic anemia.
    Gen-ID
    6708
    UniProt
    P02549
    Pathways
    Regulation of Actin Filament Polymerization
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