SLC17A7 Antikörper (C-Term)

Produktnummer ABIN1109031

Produktdetails anti-SLC17A7 Antikörper

Target: SLC17A7 (Solute Carrier Family 17 (Vesicular Glutamate Transporter), Member 7 (SLC17A7))

Bindungsspezifität: C-Term

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SLC17A7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoelectron Microscopy (IEM), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)

Spezifität: This antibody reacts with Rat 55-60 kDa VGLUT1 protein of BON cells stably expressing VGLUT1 and of total Rat brain extracts. No cross reactivity was detected with VGLUT2 and VGLUT3.

Kreuzreaktivität (Details): Species reactivity (tested):Rat.

Aufreinigung: Antigen Affinity Chromatography

Immunogen: A 17 residue synthetic peptide derived from C-terminal domain of Rat. Remarks: Vesicular Glutamate Transporter Type 1 (MW : 55-60 kD).

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.1 M Tris, 0.1 M Glycine, Glycerol 50 % , pH 7.8, 0.02 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu SLC17A7

Target: SLC17A7 (Solute Carrier Family 17 (Vesicular Glutamate Transporter), Member 7 (SLC17A7))

Andere Bezeichnung: SLC17A7 / VGLUT1 (SLC17A7 Produkte)

Synonyme: 2900052E22Rik antikoerper, AI851913 antikoerper, VGluT1 antikoerper, Vglut1 antikoerper, BNPI antikoerper, VGLUT1 antikoerper, slc17a7 antikoerper, vglut1 antikoerper, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7 antikoerper, solute carrier family 17 member 7 antikoerper, solute carrier family 17 (vesicular glutamate transporter), member 7a antikoerper, Slc17a7 antikoerper, SLC17A7 antikoerper, slc17a7a antikoerper

Hintergrund: VGLUT1 is expressed in a subset of glutamate neurons and transports glutamate into native synaptic vesicles from the brain, exhibiting a conductance for chloride that is blocked by glutamate. Vesicular glutamate transport has a substantially lower apparent affinity than the plasma membrane excitatory amino acid transporters. Glutamate transport by VGLUT1 is saturated with a K(m) of approximately 2 mM, in the same range as transport by synaptic vesicles. Finally, plasma membrane glutamate transporters recognize both aspartate and glutamate as substrates, whereas VGLUT1 does not recognize aspartate.Synonyms: BNPI, Brain-specific Na(+)-dependent inorganic phosphate cotransporter, Solute carrier family 17 member 7, Vesicular glutamate transporter 1

Gen-ID: 116638

NCBI Accession: NP_446311