Myeloperoxidase Antikörper

Produktnummer ABIN1108340

Produktdetails anti-Myeloperoxidase Antikörper

Target: Myeloperoxidase (MPO)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Myeloperoxidase Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Purified

Klon: 266-6K1

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0,1 mg/mL

Buffer: PBS, 0.02 % sodium azide, 0,1 % BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C.

Details zu Myeloperoxidase

Target: Myeloperoxidase (MPO)

Andere Bezeichnung: Myeloperoxidase (MPO Produkte)

Synonyme: mKIAA4033 antikoerper, MPO antikoerper, LOC100335032 antikoerper, POX2' antikoerper, XPOX2' antikoerper, mpo antikoerper, mpo-A antikoerper, pmr-1 antikoerper, pmr1 antikoerper, pox2 antikoerper, xpox2 antikoerper, myeloperoxidase antikoerper, myeloperoxidase L homeolog antikoerper, MPO antikoerper, Mpo antikoerper, LOC100335032 antikoerper, mpo.L antikoerper

Hintergrund: MPO is abundantly present in azurophilic granules of polymorphonuclear neutrophils. It is an important enzyme used during phagocytic lysis of engulfed foreign particles which takes part in the defence of the organism through production of hypochlorous acid (HOCl), a potent oxidant. MPO is rapidly released by activated polymorphonuclear neutrophils. Involvement of MPO has been described in numerous diseases such as atherosclerosis, lung cancer, Alzheimer's disease and multiple sclerosis. Autoimmune antibodies to MPO are involved in Wegeners disease. Since the discovery of MPO deficiency, initially regarded as rare and restricted to patients suffering from severe infections, MPO has more attracted clinical attention. In experimental studies antibodies to MPO can be used for various purposes ranging from flow cytometric analysis to detection of polymorphonuclear neutrophils in tissue sections.Synonyms: MPO

Gen-ID: 9606

UniProt: P05164

Pathways: Chromatin Binding