Myeloperoxidase Antikörper (AA 406-745)

Produktnummer ABIN3042368

Es sind 4+ Publikationen für dieses Produkt verfügbar. Der Kaninchen Polyklonal anti-Myeloperoxidase Antikörper wird verwendet zum Nachweis von Myeloperoxidase in Proben von Human. Er wurde validiert für WB, IHC und FACS.

Kurzübersicht für Myeloperoxidase Antikörper (AA 406-745) (ABIN3042368)

Target: Myeloperoxidase (MPO)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Myeloperoxidase Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)

Produktdetails anti-Myeloperoxidase Antikörper

Bindungsspezifität: AA 406-745

Verwendungszweck: Anti-Myeloperoxidase/MPO Antibody

Spezifität: No cross reactivity with other proteins.

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Homologie: Human Myeloperoxidase shares 90% amino acid (aa) sequence identity with mouse Myeloperoxidase.

Produktmerkmale: Anti-Myeloperoxidase/MPO Antibody. Tested in Flow Cytometry, IHC, WB applications. This antibody reacts with Human.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human Myeloperoxidase recombinant protein (Position:S406-S745). Human Myeloperoxidase shares 90% amino acid (aa) sequence identity with mouse Myeloperoxidase.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.1-0.5 μg/mL, Human Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-Myeloperoxidase Antikörper (ABIN3042368)

Wei, Kong, Li, Guan, Wang, Miao: "Nicotinamide mononucleotide attenuates brain injury after intracerebral hemorrhage by activating Nrf2/HO-1 signaling pathway." in: Scientific reports, Vol. 7, Issue 1, pp. 717, (2018) (PubMed).

Xu, Zhang, He, Li, Gao, Liu: "Lactobacillus acidophilus alleviates pouchitis after ileal pouch-anal anastomosis in rats." in: World journal of gastroenterology, Vol. 23, Issue 26, pp. 4735-4743, (2018) (PubMed).

Wang, Liu, Liu, Wang, Fan, Ma, Jin, Xiang, Huang, Zhang, Xu, Yin, He: "Interleukin-17A Aggravates Middle Ear Injury Induced by Streptococcus pneumoniae through the p38 Mitogen-Activated Protein Kinase Signaling Pathway." in: Infection and immunity, Vol. 85, Issue 10, (2017) (PubMed).

Yu, Chen, Wang, Kuang, Liu, Zhang, Du: "Neuroprotective effect of kaempferol glycosides against brain injury and neuroinflammation by inhibiting the activation of NF-?B and STAT3 in transient focal stroke." in: PLoS ONE, Vol. 8, Issue 2, pp. e55839, (2013) (PubMed).

Details zu Myeloperoxidase

Target: Myeloperoxidase (MPO)

Andere Bezeichnung: MPO

Hintergrund:

Background: Myeloperoxidase (MPO) is a mammalian phagocyte hemoprotein thought to primarily mediate host defense reactions. It is abundantly expressed in neutrophils and secreted during their activation. Myeloperoxidase is part of the host defense system of human polymorphonuclear leukocytes, responsible for microbicidal activity against a wide range of organisms. It is located in the nucleus as well as in the cytoplasm. Intranuclear MPO may help to protect DNA against damage resulting from oxygen radicals produced during myeloid cell maturation and function. The standard product used in this kit is the product of gene recombination, consisting of 697 (A49-S745) amino acids with the molecular mass of 80KDa.

Gene Full Name: myeloperoxidase

Sequence Similarities: Belongs to the peroxidase family. XPO subfamily.

Molekulargewicht: 60-65 kDa, 80-90 kDa

Gen-ID: 4353

UniProt: P05164

Pathways: Chromatin Binding