IFITM1 Antikörper (N-Term)

Produktnummer ABIN1106094

Produktdetails anti-IFITM1 Antikörper

Target: IFITM1 (Interferon-Induced Transmembrane Protein 1 (IFITM1))

Bindungsspezifität: N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IFITM1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Spezifität: This antibody detects CD225 / IFITM1 (N-term).

Kreuzreaktivität (Details): Species reactivity (tested):Human

Aufreinigung: Immunogen affinity purified

Immunogen: Synthetic peptide corresponding to a sequence at the N-terminal of human IFITM1 .Remarks: Sequence is identical to the related rat and mouse sequence.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Buffer: 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3

Konservierungsmittel: Sodium azide, Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Sodium azide and Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Details zu IFITM1

Target: IFITM1 (Interferon-Induced Transmembrane Protein 1 (IFITM1))

Andere Bezeichnung: CD225 / IFITM1 (IFITM1 Produkte)

Synonyme: 9-27 antikoerper, CD225 antikoerper, DSPA2a antikoerper, IFI17 antikoerper, LEU13 antikoerper, 1110036C17Rik antikoerper, Mil-2 antikoerper, Mil2 antikoerper, interferon induced transmembrane protein 1 antikoerper, interferon induced transmembrane protein 1 (9-27) antikoerper, Ifitm1 antikoerper, IFITM1 antikoerper

Hintergrund: Interferon-induced Transmembrane Protein 1 (IFITM1), also called Interferon-induced Protein 17 (IFI17). IFITM1 activity is required for primordial germ cells (PGCs) transit from the mesoderm into the endoderm, and that it appears to act via a repulsive mechanism, such that PGCs avoid Ifitm1-expressing tissues. It is mapped to Chr.11 and belongs to the family of interferon-induced transmembrane proteins (Ifitm/mil/fragilis), which encodes cell surface proteins that may modulate cell adhesion and influence cell differentiation. Interferon-inducible membrane proteins of approximately 17 kDa have been suggested to play a role in the antiproliferative activity of interferons based on their pattern of induction in interferon-sensitive and -resistant cell lines and the ability of a membrane fraction enriched in 17- kDa proteins to inhibit cell growth.Synonyms: IFI17, Interferon-induced protein 17, Interferon-induced transmembrane protein 1, Interferon-inducible protein 9-27, Leu-13 antigen

Gen-ID: 8519

NCBI Accession: NP_003632

UniProt: P13164