CD21 Antikörper

Produktnummer ABIN1106058

Produktdetails anti-CD21 Antikörper

Target: CD21 (CR2) (Complement Component (3d/Epstein Barr Virus) Receptor 2 (CR2))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD21 Antikörper ist unkonjugiert

Applikation: Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Ig Fraction

Immunogen: A BALB/c mouse was immunized subcutaneously in its footpads with fragments of a Human tonsil. After fusing the lymphocytes from the popliteal lymph nodes of this mouse with murine SP2/0 myeloma cells

Klon: 4C5

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 60 μg Ig/ml

Buffer: 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for Three months or (in aliquots) at -20 °C for longer.

Details zu CD21

Target: CD21 (CR2) (Complement Component (3d/Epstein Barr Virus) Receptor 2 (CR2))

Andere Bezeichnung: CD21 (CR2 Produkte)

Synonyme: C3DR antikoerper, CD21 antikoerper, CR antikoerper, CVID7 antikoerper, SLEB9 antikoerper, Cd21 antikoerper, cd21 antikoerper, CR1 antikoerper, CR1-L antikoerper, CR2 antikoerper, complement C3d receptor 2 antikoerper, complement C3b/C4b receptor 1 (Knops blood group) antikoerper, CR2 antikoerper, Cr2 antikoerper, CR1 antikoerper

Hintergrund: CD21 is a type I integral membrane glycoprotein that serves as a receptor for the C3d complement fragment and for the Epstein-Barr virus. It plays a role in B cell activation and proliferation and undergoes phosphorylation after B cell activation with phorbol esters. CD21 is expressed on mature B cells, follicular Dendritic cells, pharyngeal and cervical epithelial cells and a subset of thymocytes. The adaptive immune response is tightly regulated to limit responding cells in an antigen-specific manner. On B cells, co-receptors CD21/CD19 modulate the strength of B cell Ag receptor (BCR) signals, thereby influencing cell fate. Complement receptor (CR) type 2 (CR2/ CD21) is normally expressed during the immature and mature stages of B cell development. In association with CD19, CR21 plays an important role in enhancing mature B cell responses to foreign antigen.Synonyms: C3DR, C3d receptor, CR2, Complement C3d receptor, Complement receptor type 2, Dendritic Cell Marker, EBV Receptor, Epstein-Barr virus receptor

Molekulargewicht: 145 kDa

Gen-ID: 9606

UniProt: P20023

Pathways: Komplementsystem