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ABI1 Antikörper (C-Term)
ABI1
Reaktivität: Human, Ratte, Maus
WB, IHC (p), IF, IHC (fro)
Wirt: Kaninchen
Polyclonal
unconjugated
Produktnummer ABIN1105192
Produktdetails anti-ABI1 Antikörper
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Target
Alle ABI1 Antikörper anzeigen
ABI1
(Abl-Interactor 1 (ABI1))
Bindungsspezifität
Alle Epitope für ABI1 Antikörper
C-Term
Reaktivität
Alle Reaktivitäten für ABI1 Antikörper
Human, Ratte, Maus
Wirt
Alle Wirte für ABI1 Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für ABI1 Antikörper
Polyklonal
Konjugat
Alle Konjugate für ABI1 Antikörper
Dieser ABI1 Antikörper ist unkonjugiert
Applikation
Alle Applikationen für ABI1 Antikörper
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))
Spezifität
This antibody detects ABI1 / SSH3BP1 (C-term).
Kreuzreaktivität (Details)
Species reactivity (tested):Human, mouse, rat
Aufreinigung
Immunogen affinity purified
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminal of human ABI-1 .Remarks: Sequence is different from the related rat and mouse sequence by single amino acid
Isotyp
IgG
Top Product
Discover our top product ABI1 Primärantikörper
Alternativen
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Anwendungsinformationen
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Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Rekonstitution
0.2 mL of distilled water will yield a concentration of 500 μg/mL.
Buffer
5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3
Konservierungsmittel
Sodium azide, Thimerosal (Merthiolate)
Vorsichtsmaßnahmen
This product contains Sodium azide and Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Handhabung
Avoid repeated freezing and thawing.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
Details zu ABI1
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Target
ABI1
(Abl-Interactor 1 (ABI1))
Andere Bezeichnung
ABI1 / SSH3BP1 (ABI1 Produkte )
Synonyme
ABI-1 antikoerper, ABLBP4 antikoerper, E3B1 antikoerper, NAP1BP antikoerper, SSH3BP antikoerper, SSH3BP1 antikoerper, NAP1 antikoerper, Ssh3bp1 antikoerper, E3b1 antikoerper, abi1 antikoerper, wu:fc66g09 antikoerper, wu:fk56a10 antikoerper, zgc:73174 antikoerper, MGC84356 antikoerper, ABI1 antikoerper, abi-1 antikoerper, e3b1 antikoerper, nap1bp antikoerper, ssh3bp antikoerper, ssh3bp1 antikoerper, wu:fe48a10 antikoerper, zgc:153534 antikoerper, DKFZp469P1319 antikoerper, abl interactor 1 antikoerper, abl-interactor 1 antikoerper, abl-interactor 1a antikoerper, abl interactor 1 S homeolog antikoerper, abl-interactor 1b antikoerper, Abl-interactor 1 antikoerper, Abl interactor 1 antikoerper, ABI1 antikoerper, Abi1 antikoerper, abi1a antikoerper, abi1.S antikoerper, abi1 antikoerper, abi1b antikoerper, Bm1_44660 antikoerper, LOAG_04356 antikoerper
Hintergrund
ABI1 is a human homolog of mouse Abl-interactor-1 (Abi1), mapped on 10p11.2. ABI1 participate in the transduction of signals from Ras to Rac by regulating Rac-specific guanine nucleotide exchange factor (GEF) activities. ABI1 dramatically promoted ABL1-mediated tyrosine phosphorylation of MENA,but not of other substrates. Abi-1 regulates c-Abl-mediated phosphorylation of Mena by interacting with both proteins.ABI1 plays a role in the leukemogenesis by translocating to MLL.Synonyms: Abelson interactor 1, Abi-1, Abl interactor 1, Abl-binding protein 4, AblBP4, Eps8 SH3 domain-binding protein, Nap1-binding protein, Spectrin SH3 domain-binding protein 1, Spectrin binding protein, e3B1
Gen-ID
10006
NCBI Accession
NP_001012768
UniProt
Q8IZP0
Pathways
RTK Signalweg , Response to Water Deprivation , ER-Nucleus Signaling
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